A New Method for Production of the Sr-82 Generator Radionuclide and Other Medical Radionuclides

• Published in: Technical physics Vol. 63; no. 9; pp. 1254 - 1261
• Main Authors: Panteleev, V. N., Barzakh, A. E., Batist, L. Kh, Fedorov, D. V., Ivanov, V. S., Krotov, S. A., Molkanov, P. L., Orlov, S. Yu, Seliverstov, M. D., Volkov, Yu. M.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-09-2018; Springer; Springer Nature B.V
• Subjects: 07 ISOTOPES AND RADIATION SOURCES; ACTINIUM 225; ALPHA DECAY; Classical and Continuum Physics; COPPER 67; CYCLOTRONS; DESIGN; DIAGNOSIS; ION BEAMS; MEV RANGE 10-100; Nuclear physics; Physical Approaches and Problems of Data Interpretation in the Life Sciences; Physics; Physics and Astronomy; PROTONS; RADIOISOTOPE GENERATORS; Radioisotopes; RADIOTHERAPY; RADIUM 223; RADIUM 224; STRONTIUM 82; Target Substrate; Petersburg Nuclear Physics Institute; Irradiated Target Material; 64Cu Production; Mass Separation
• ISSN: 1063-7842; 1090-6525
• DOI: 10.1134/S1063784218090153

A cyclotron (C-80) designed to produce protons with an energy of 40–80 MeV and beam intensity of 100–200 μA has been launched at the Petersburg Nuclear Physics Institute, National Research Center Kurchatov Institute. The main task of C-80 is the production of a wide range of medical radionuclides for diagnosis and therapy. A complex named Radioactive Isotopes on the C-80 Cyclotron (RIC-80) and intended to function on the C-80 beam was developed for this purpose. A brief description of the RIC-80 complex is given, and the results of the use of new methods and studies of target devices for the production of the generator radioisotope
82
Sr;
223
Ra,
224
Ra, and
225
Ac radioisotopes that undergo alpha-decay;
67
Cu; and other medical radionuclides are presented. The use of a mass separator in the “on-line” mode to obtain ion beams of high-purity radioisotopes is a distinctive feature of the complex used in the project, and it is especially important for medical applications.