Comparative efficacy of novel combination strategies for unresectable hepatocellular carcinoma: A network metanalysis of phase III trials

Dual programmed cell death-1 and vascular endothelial growth factor pathway inhibition is the novel standard of care for patients with unresectable hepatocellular carcinoma. Direct comparisons between first-line treatments are lacking. We conducted a literature search in MEDLINE (https://pubmed.ncbi...

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Bibliographic Details
Published in:	European journal of cancer (1990) Vol. 174; pp. 57 - 67
Main Authors:	Fulgenzi, Claudia A.M., D'Alessio, Antonio, Airoldi, Chiara, Scotti, Lorenza, Demirtas, Coskun O., Gennari, Alessandra, Cortellini, Alessio, Pinato, David J.
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-10-2022 Elsevier Science Ltd
Subjects:	Apoptosis Bevacizumab Cell death Clinical trials CTLA-4 Effectiveness Growth factors Hepatocellular cancer Hepatocellular carcinoma Immune checkpoint inhibitors Immunotherapy Inhibitors Kinases Literature reviews Liver cancer Meta-analysis Mortality PD-1 Protein-tyrosine kinase Regression analysis Regression models Risk Risk reduction Statistical analysis Survival Tyrosine Vascular endothelial growth factor VEGF Immunotherapy VEGF Clinical trials CTLA-4 Survival PD-1 Hepatocellular cancer
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