Practice guidelines for management of uterine corpus cancer in Korea: a Korean Society of Gynecologic Oncology consensus statement

The Korean Society of Gynecologic Oncology (KSGO) had been making an effort to standardize and enhance the quality of domestic uterine corpus cancer treatment by developing updated clinical practice guidelines in 2021. The KSGO revised the guidelines based on a literature search using 4 key elements...

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Published in:Journal of gynecologic oncology Vol. 35; no. 2; p. e45
Main Authors: Kim, Ju-Hyun, Kim, Dae-Yeon, Kim, Junhwan, Noh, Joseph J, Hwang, Woo Yeon, Baek, Min-Hyun, Choi, Min Chul, Joo, Won Duk, Lee, Yong Jae, Suh, Dong Hoon, Kim, Yong Beom
Format: Journal Article
Language:English
Published: Korea (South) Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 01-03-2024
대한부인종양학회
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Abstract The Korean Society of Gynecologic Oncology (KSGO) had been making an effort to standardize and enhance the quality of domestic uterine corpus cancer treatment by developing updated clinical practice guidelines in 2021. The KSGO revised the guidelines based on a literature search using 4 key elements: Population, Intervention, Comparison, and Outcome framework. These elements include the evaluation of the efficacy and safety of immune checkpoint inhibitor treatment in recurrent/advanced endometrial cancer patients who have failed platinum-based chemotherapy, as well as the effect of combined treatment with trastuzumab in patients with HER2/neu-positive endometrial cancer. Additionally, the guideline assessed the efficacy and safety of omitting lymph node dissection in low-risk endometrial cancer patients, investigated the effect of sentinel lymph node mapping in early-stage endometrial cancer surgery, addressed the outcome of chemoradiation therapy as a postoperative treatment in patients with advanced (stage III-IVA) endometrial cancer, and explored the impact of initial treatment with immune checkpoint inhibitors on survival in patients with advanced or recurrent endometrial cancer patients.
AbstractList The Korean Society of Gynecologic Oncology (KSGO) had been making an effort tostandardize and enhance the quality of domestic uterine corpus cancer treatment bydeveloping updated clinical practice guidelines in 2021. The KSGO revised the guidelinesbased on a literature search using 4 key elements: Population, Inter vention, Comparison,and Outcome framework. These elements include the evaluation of the efficacy and safety ofimmune checkpoint inhibitor treatment in recurrent/advanced endometrial cancer patientswho have failed platinum-based chemotherapy, as well as the effect of combined treatmentwith trastuzumab in patients with HER2/neu-positive endometrial cancer. Additionally,the guideline assessed the efficacy and safety of omitting lymph node dissection in low-riskendometrial cancer patients, investigated the effect of sentinel lymph node mapping inearly-stage endometrial cancer surger y, addressed the outcome of chemoradiation therapy asa postoperative treatment in patients with advanced (stage III–IVA) endometrial cancer, andexplored the impact of initial treatment with immune checkpoint inhibitors on sur vival inpatients with advanced or recurrent endometrial cancer patients. KCI Citation Count: 0
The Korean Society of Gynecologic Oncology (KSGO) had been making an effort to standardize and enhance the quality of domestic uterine corpus cancer treatment by developing updated clinical practice guidelines in 2021. The KSGO revised the guidelines based on a literature search using 4 key elements: Population, Intervention, Comparison, and Outcome framework. These elements include the evaluation of the efficacy and safety of immune checkpoint inhibitor treatment in recurrent/advanced endometrial cancer patients who have failed platinum-based chemotherapy, as well as the effect of combined treatment with trastuzumab in patients with HER2/neu-positive endometrial cancer. Additionally, the guideline assessed the efficacy and safety of omitting lymph node dissection in low-risk endometrial cancer patients, investigated the effect of sentinel lymph node mapping in early-stage endometrial cancer surgery, addressed the outcome of chemoradiation therapy as a postoperative treatment in patients with advanced (stage III–IVA) endometrial cancer, and explored the impact of initial treatment with immune checkpoint inhibitors on survival in patients with advanced or recurrent endometrial cancer patients. The committee of uterine corpus cancer of the Korean Society of Gynecologic Oncology developed updated guideline for treatments of uterine corpus cancer patients. Evidences of recommendation according to each key question were evaluated using systematic review and meta-analysis.
The Korean Society of Gynecologic Oncology (KSGO) had been making an effort to standardize and enhance the quality of domestic uterine corpus cancer treatment by developing updated clinical practice guidelines in 2021. The KSGO revised the guidelines based on a literature search using 4 key elements: Population, Intervention, Comparison, and Outcome framework. These elements include the evaluation of the efficacy and safety of immune checkpoint inhibitor treatment in recurrent/advanced endometrial cancer patients who have failed platinum-based chemotherapy, as well as the effect of combined treatment with trastuzumab in patients with HER2/neu-positive endometrial cancer. Additionally, the guideline assessed the efficacy and safety of omitting lymph node dissection in low-risk endometrial cancer patients, investigated the effect of sentinel lymph node mapping in early-stage endometrial cancer surgery, addressed the outcome of chemoradiation therapy as a postoperative treatment in patients with advanced (stage III-IVA) endometrial cancer, and explored the impact of initial treatment with immune checkpoint inhibitors on survival in patients with advanced or recurrent endometrial cancer patients.
Author Noh, Joseph J
Suh, Dong Hoon
Kim, Dae-Yeon
Kim, Junhwan
Choi, Min Chul
Baek, Min-Hyun
Kim, Yong Beom
Hwang, Woo Yeon
Joo, Won Duk
Lee, Yong Jae
Kim, Ju-Hyun
AuthorAffiliation 4 Center for Gynecologic Cancer, National Cancer Center, Goyang, Korea
2 Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
3 Department of Obstetrics and Gynecology, School of Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Korea
5 Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, College of Medicine, CHA University, Seongnam, Korea
7 Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea
6 Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea
1 Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
AuthorAffiliation_xml – name: 3 Department of Obstetrics and Gynecology, School of Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, Korea
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– name: 5 Comprehensive Gynecologic Cancer Center, CHA Bundang Medical Center, College of Medicine, CHA University, Seongnam, Korea
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  givenname: Min-Hyun
  orcidid: 0000-0003-0423-9038
  surname: Baek
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  givenname: Min Chul
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  givenname: Won Duk
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  givenname: Yong Jae
  orcidid: 0000-0003-0297-3116
  surname: Lee
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  givenname: Dong Hoon
  orcidid: 0000-0002-4312-966X
  surname: Suh
  fullname: Suh, Dong Hoon
  organization: Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea
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  givenname: Yong Beom
  orcidid: 0000-0003-1196-369X
  surname: Kim
  fullname: Kim, Yong Beom
  organization: Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea
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10.1056/NEJMoa2216334
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Issue 2
Keywords Sentinel Lymph Node
Immune Checkpoint Inhibitor
Survival
Surgery
Endometrial Neoplasm
Trastuzumab
Language English
License 2024. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology, and Japan Society of Gynecologic Oncology.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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대한부인종양학회
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Snippet The Korean Society of Gynecologic Oncology (KSGO) had been making an effort to standardize and enhance the quality of domestic uterine corpus cancer treatment...
The Korean Society of Gynecologic Oncology (KSGO) had been making an effort tostandardize and enhance the quality of domestic uterine corpus cancer treatment...
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SubjectTerms Endometrial Neoplasms - pathology
Female
Humans
Lymph Node Excision
Lymph Nodes - pathology
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Practice Guideline
Republic of Korea
Sentinel Lymph Node - pathology
Sentinel Lymph Node Biopsy
Uterine Neoplasms - pathology
산부인과학
Title Practice guidelines for management of uterine corpus cancer in Korea: a Korean Society of Gynecologic Oncology consensus statement
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Volume 35
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ispartofPNX Journal of Gynecologic Oncology, 2024, 35(2), , pp.1-13
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