The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be incre...

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Bibliographic Details
Published in:	Comptes rendus. Chimie Vol. 25; no. G1; pp. 295 - 306
Main Authors:	Hui, Khee Chung, Dhanapalan, Nagaammai, Khayrani, Apriliana Cahya, Imanto, Teguh, Sambudi, Nonni Soraya
Format:	Journal Article
Language:	English
Published:	Académie des sciences 01-01-2022
Subjects:	Acetaminophen Carbon quantum dots Chitosan Drug delivery Hydroxyapatite
Online Access:	Get full text
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Summary:	Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m$^{2}$/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.
ISSN:	1878-1543 1878-1543
DOI:	10.5802/crchim.206