OECD validation of the rodent Hershberger assay using three reference chemicals; 17α-methyltestosterone, procymidone, and p, p'-DDE

The rodent Hershberger assay is being validated as an in vivo test method for detecting androgenic or antiandrogenic compounds by the Organization for Economic Cooperation and Development (OECD). As part of the international validation work, we studied 17α-methyltestosterone for evaluating androgeni...

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Bibliographic Details
Published in:	Archives of toxicology Vol. 81; no. 5; pp. 309 - 318
Main Authors:	SHIN, Jae-Ho, HYUN JU MOON, IL HYUN KANG, TAE SUNG KIM, SU JUNG LEE, JI YOUN AHN, BAE, Hoon, EUI BAE JEUNG, SOON YOUNG HAN
Format:	Journal Article
Language:	English
Published:	Berlin Springer 01-05-2007 Springer Nature B.V
Subjects:	Antiandrogenic activity Assaying Biocompatibility Biological and medical sciences Biomedical materials Castration Chemicals DDE In vivo methods and tests Medical sciences Methyltestosterone Nitrous oxide Pesticides, fertilizers and other agrochemicals toxicology Procymidone Propionic acid Rodents Sex Testosterone Testosterone propionate Toxicity Toxicology Antineoplastic agent Validation Evaluation Methyltestosterone Insecticide Androgen DDE p,p'-DDE Chemical compound Reference Pesticides Rodentia Hershberger assay 17α-methyltestosterone· Procymidone Vertebrata Mammalia Organochlorine compounds Animal Sex steroid hormone OECD evaluation
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