Neural networks that co-ordinate locomotion and body orientation in lamprey
The networks of the brainstem and spinal cord that co-ordinate locomotion and body orientation in lamprey are described. The cycle-to-cycle pattern generation of these networks is produced by interacting glutamatergic and glycinergic neurones, with NMDA receptor—channels playing an important role at...
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Published in: | Trends in Neurosciences Vol. 18; no. 6; pp. 270 - 279 |
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Main Authors: | , , , , , , , |
Format: | Book Review Journal Article |
Language: | English |
Published: |
Oxford
Elsevier Ltd
1995
Elsevier Science |
Subjects: | |
Online Access: | Get full text |
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Summary: | The networks of the brainstem and spinal cord that co-ordinate locomotion and body orientation in lamprey are described. The cycle-to-cycle pattern generation of these networks is produced by interacting glutamatergic and glycinergic neurones, with NMDA receptor—channels playing an important role at lower rates of locomotion. The fine tuning of the networks produced by 5-HT, dopamine and GABA systems involves a modulation of Ca
2+-dependent K
+ channels, high- and low-threshold voltage-activated Ca
2+ channels and presynaptic inhibitory mechanisms. Mathematical modelling has been used to explore the capacity of these biological networks. The vestibular control of body orientation during swimming is exerted via reticulospinal neurones located in different reticular nuclei. These neurones become activated maximally at different angles of tilt. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0166-2236 1878-108X |
DOI: | 10.1016/0166-2236(95)80008-P |