Melatonin as a promising agent to treat ovarian cancer: molecular mechanisms

Ovarian cancer (OC) has the highest mortality rate of all gynecological cancers, and most patients develop chemoresistance after first-line treatments. Despite recent advances, the 5-year relative survival is ~45% for all OC subtypes, and invasive epithelial OC has only a 17% survival rate when diag...

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Bibliographic Details

Published in:	Carcinogenesis (New York) Vol. 38; no. 10; pp. 945 - 952
Main Authors:	Chuffa, Luiz Gustavo de Almeida, Reiter, Russel J, Lupi, Luiz Antonio
Format:	Journal Article
Language:	English
Published:	England 01-10-2017
Subjects:	Antineoplastic Agents - pharmacology Apoptosis - drug effects Female Humans Melatonin - pharmacology Melatonin - physiology Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology Signal Transduction - drug effects
Online Access:	Get full text
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