Thiopurine S-methyltransferase pharmacogenetics: genotype to phenotype correlation in the Slovenian population

The toxicity of thiopurine drugs has been correlated to the activity of thiopurine S-methyltransferase (TPMT), whose interindividual variation is a consequence of genetic polymorphisms. We have herein investigated the relevance of some genetic markers for the prediction of thiopurine-related toxicit...

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Bibliographic Details

Published in:	Pharmacology Vol. 77; no. 3; p. 105
Main Authors:	Milek, M, Murn, J, Jaksic, Z, Lukac Bajalo, J, Jazbec, J, Mlinaric Rascan, I
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-2006
Subjects:	DNA - genetics Gene Frequency Genotype Humans Methyltransferases - genetics Methyltransferases - metabolism Pharmacogenetics Phenotype Purines - metabolism Slovenia Slovenia
Online Access:	Get more information
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