Synthesis of some 6,8-diarylimidazo[1,2-a]pyrazine derivatives by using either reflux or microwave irradiation method and investigation of their anticancer activities

In order to obtain some 6,8‐diarylimidazo[1,2‐a]pyrazines, 1‐(2‐aryl‐2‐oxoethyl)‐2‐aryloylimidazole derivatives were reacted with ammonium acetate in acetic acid by using a new method different from that found in the literature. Anticancer activities of the compounds obtained were evaluated and the...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry Vol. 42; no. 2; pp. 319 - 325
Main Authors: Demirayak, Seref, Kayagil, Ismail
Format: Journal Article
Language:English
Published: Hoboken Wiley-Blackwell 01-03-2005
Wiley‐Blackwell
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Summary:In order to obtain some 6,8‐diarylimidazo[1,2‐a]pyrazines, 1‐(2‐aryl‐2‐oxoethyl)‐2‐aryloylimidazole derivatives were reacted with ammonium acetate in acetic acid by using a new method different from that found in the literature. Anticancer activities of the compounds obtained were evaluated and the noticeable activity values were reported.
Bibliography:istex:D0C828CBCB5A86193E81821654CD833D7B918DE1
ArticleID:JHET5570420224
ark:/67375/WNG-SVH3PQZR-7
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570420224