Influence of different levels and sources of copper supplementation on performance, some blood parameters, nutrient digestibility and mineral balance in lambs

Two trials were conducted in a 2×2+1 factorial experiment based on a completely randomized design to evaluate the effects of different sources of copper (Cu) on performance, plasma metabolites, nutrient digestibility and retention of some minerals in male lambs on a barley based diet. The first tria...

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Bibliographic Details
Published in:Livestock science Vol. 147; no. 1-3; pp. 9 - 19
Main Authors: Dezfoulian, Amir Hossein, Aliarabi, Hassan, Tabatabaei, Mohammad Mehdi, Zamani, Pouya, Alipour, Daryoush, Bahari, Aliasghar, Fadayifar, Amir
Format: Journal Article
Language:English
Published: Elsevier B.V 01-08-2012
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Summary:Two trials were conducted in a 2×2+1 factorial experiment based on a completely randomized design to evaluate the effects of different sources of copper (Cu) on performance, plasma metabolites, nutrient digestibility and retention of some minerals in male lambs on a barley based diet. The first trial consisted of 25 lambs (6–7 months of age) which were randomly allotted to 5 treatments including, (1) basal diet (containing 8.6mg Cu/kg DM; control) without supplementary Cu; (2) basal diet+10mg Cu/kg DM as CuSO4 (Cu–S 10); (3) basal diet+20mg Cu/kg DM as CuSO4 (Cu–S 20); (4) basal diet+10mg Cu/kg DM as Cu-proteinate (Cu–P 10); and (5) basal diet+20mg Cu/kg DM as Cu-proteinate (Cu–P 20). The basal diet consisted of 70% barley grain, 27% alfalfa hay and 3% soybean meal. Blood samples were taken via the jugular vein on 0, 7, 14, 28, 57, 65 and 84d and analyzed for serum ceruloplasmin, total antioxidant capacity, red blood cell superoxide dismutase activity, erythrocyte count, packed cell volume, hemoglobin and plasma mineral concentrations. For the second trial, 4 lambs from each treatment were randomly selected and transferred to metabolic cages to evaluate the effects of different Cu sources on nutrient digestibility and Cu, zinc (Zn), and nitrogen (N) retentions. Copper source had a significant effect on ceruloplasmin concentration (P<0.05). At 65d the 20ppm Cu-proteinate treatment had the highest ceruloplasmin concentration (P<0.05). Copper source and level had no significant effect on superoxide dismutase activity (P>0.05). Total antioxidant capacity increased (P<0.05) from 0 to 65d but there were no significant differences between treatments on either day (P>0.05). No clinical signs of copper toxicity were observed in this study, although we speculate that the continuance of treatments would have produced copper toxicity and hence hemolytic anemia.
Bibliography:http://dx.doi.org/10.1016/j.livsci.2012.03.011
ISSN:1871-1413
1878-0490
DOI:10.1016/j.livsci.2012.03.011