Effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats
Objective To evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats. Methodology In total, 32 male Wistar rats were divided into four groups (n = 8): AP—induced apical periodontitis; S—cigarette smoke inhalation; APS—induced...
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| Published in: | International endodontic journal Vol. 56; no. 12; pp. 1559 - 1570 |
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| Format: | Journal Article |
| Language: | English |
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Chichester
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01-12-2023
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| Abstract | Objective
To evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats.
Methodology
In total, 32 male Wistar rats were divided into four groups (n = 8): AP—induced apical periodontitis; S—cigarette smoke inhalation; APS—induced AP and cigarette smoke inhalation; and C (control)—neither AP nor cigarette smoke inhalation. To induce cigarette smoke inhalation, the animals were kept in a chamber filled with tobacco smoke for 8 min thrice a day for 50 days. AP was induced 20 days after inhalation initiation by exposing their coronary pulp to their oral environment for 30 days. After animals were euthanized, their right hemimaxillae were removed for histopathological, semi‐quantitative and immunohistochemical (F4/80, CD206 and iNOS) analyses.
Results
Quantitative data showed a moderate number of inflammatory infiltrates in AP and an intense number in APS (p < .05). Comparing F4/80+ cells showed no statistically significant differences among groups, but we found more CD206+ cells in AP than in C and S (p > .05). INOS+ immunostaining showed a significant increase in AP and APS, when compared with C and S (p < .05). APS had more iNOS+ cells than AP (p < .05).
Conclusion
Cigarette smoke inhalation worsened AP, leading to a predominantly pro‐ inflammatory profile in our experimental model. |
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| AbstractList | ObjectiveTo evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats.MethodologyIn total, 32 male Wistar rats were divided into four groups (n = 8): AP—induced apical periodontitis; S—cigarette smoke inhalation; APS—induced AP and cigarette smoke inhalation; and C (control)—neither AP nor cigarette smoke inhalation. To induce cigarette smoke inhalation, the animals were kept in a chamber filled with tobacco smoke for 8 min thrice a day for 50 days. AP was induced 20 days after inhalation initiation by exposing their coronary pulp to their oral environment for 30 days. After animals were euthanized, their right hemimaxillae were removed for histopathological, semi‐quantitative and immunohistochemical (F4/80, CD206 and iNOS) analyses.ResultsQuantitative data showed a moderate number of inflammatory infiltrates in AP and an intense number in APS (p < .05). Comparing F4/80+ cells showed no statistically significant differences among groups, but we found more CD206+ cells in AP than in C and S (p > .05). INOS+ immunostaining showed a significant increase in AP and APS, when compared with C and S (p < .05). APS had more iNOS+ cells than AP (p < .05).ConclusionCigarette smoke inhalation worsened AP, leading to a predominantly pro‐ inflammatory profile in our experimental model. Objective To evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats. Methodology In total, 32 male Wistar rats were divided into four groups (n = 8): AP—induced apical periodontitis; S—cigarette smoke inhalation; APS—induced AP and cigarette smoke inhalation; and C (control)—neither AP nor cigarette smoke inhalation. To induce cigarette smoke inhalation, the animals were kept in a chamber filled with tobacco smoke for 8 min thrice a day for 50 days. AP was induced 20 days after inhalation initiation by exposing their coronary pulp to their oral environment for 30 days. After animals were euthanized, their right hemimaxillae were removed for histopathological, semi‐quantitative and immunohistochemical (F4/80, CD206 and iNOS) analyses. Results Quantitative data showed a moderate number of inflammatory infiltrates in AP and an intense number in APS (p < .05). Comparing F4/80+ cells showed no statistically significant differences among groups, but we found more CD206+ cells in AP than in C and S (p > .05). INOS+ immunostaining showed a significant increase in AP and APS, when compared with C and S (p < .05). APS had more iNOS+ cells than AP (p < .05). Conclusion Cigarette smoke inhalation worsened AP, leading to a predominantly pro‐ inflammatory profile in our experimental model. |
| Author | Vasques, Ana Maria Veiga Bueno, Carlos Roberto Emerenciano Dezan‐Junior, Eloi Cintra, Luciano Tavares Ângelo Ervolino, Edilson Biguetti, Claudia Cristina Matsumoto, Mariza Akemi Silva, Ana Claudia Rodrigues |
| Author_xml | – sequence: 1 givenname: Ana Claudia Rodrigues orcidid: 0000-0002-7570-6126 surname: Silva fullname: Silva, Ana Claudia Rodrigues organization: Universidade Estadual Paulista (UNESP) – sequence: 2 givenname: Ana Maria Veiga orcidid: 0000-0002-1211-2363 surname: Vasques fullname: Vasques, Ana Maria Veiga organization: Universidade Estadual Paulista (UNESP) – sequence: 3 givenname: Carlos Roberto Emerenciano orcidid: 0000-0002-1897-2823 surname: Bueno fullname: Bueno, Carlos Roberto Emerenciano organization: Universidade Estadual Paulista (UNESP) – sequence: 4 givenname: Edilson surname: Ervolino fullname: Ervolino, Edilson organization: Universidade Estadual Paulista (UNESP) – sequence: 5 givenname: Luciano Tavares Ângelo orcidid: 0000-0003-2348-7846 surname: Cintra fullname: Cintra, Luciano Tavares Ângelo organization: Universidade Estadual Paulista (UNESP) – sequence: 6 givenname: Claudia Cristina surname: Biguetti fullname: Biguetti, Claudia Cristina organization: University of Texas Rio Grande Valley – sequence: 7 givenname: Mariza Akemi surname: Matsumoto fullname: Matsumoto, Mariza Akemi organization: Universidade Estadual Paulista (UNESP) – sequence: 8 givenname: Eloi surname: Dezan‐Junior fullname: Dezan‐Junior, Eloi email: eloi.dezan@unesp.br organization: Universidade Estadual Paulista (UNESP) |
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| CitedBy_id | crossref_primary_10_1016_j_joen_2024_01_005 |
| Cites_doi | 10.1016/j.it.2004.09.015 10.1016/j.surg.2004.04.001 10.1016/S0099‐2399(81)80125‐2 10.1034/j.1399‐6576.2002.460806.x 10.1007/s005990070005 10.1016/j.joen.2017.12.008 10.1902/jop.2007.060296 10.1111/j.1600‐0722.2004.00112.x 10.1016/j.msec.2019.110229 10.1007/s11999‐016‐5184‐6 10.1111/jre.12584 10.1111/j.1600‐0765.2009.01262.x 10.1007/s00784‐017‐2123‐1 10.1177/0022034518805984 10.1016/j.jds.2018.12.002 10.1590/1807‐3107bor‐2018.vol32.0068 10.1016/j.joen.2006.12.025 10.3390/cells10030671 10.3389/fimmu.2015.00212 10.1067/moe.2000.107059 10.1371/journal.pone.0232731 10.1016/j.archoralbio.2021.105266 10.1177/154405910808701207 10.1007/s00784‐017‐2062‐x 10.1016/j.sdentj.2018.09.006 10.1034/j.1600‐0528.2003.00032.x 10.1902/jop.2006.050190 10.1016/j.joen.2021.01.010 10.1111/iej.13883 10.1111/iej.13633 10.1111/iej.13519 10.1007/s00784‐020‐03324‐2 10.1016/j.intimp.2013.10.022 10.1902/jop.2000.71.1.58 10.1016/j.joen.2011.03.004 10.1111/iej.13257 10.1590/1807‐3107bor‐2019.vol33.0047 10.1165/rcmb.2015‐0012OC 10.1034/j.1600‐9657.2000.016001001.x 10.1177/0022034511401405 10.1590/1678‐775720140140 10.1111/j.1365‐2591.2007.01224.x 10.1016/S0099‐2399(96)80266‐4 10.1111/iej.13477 10.1186/s12931‐017‐0522‐0 10.1016/j.joen.2012.02.011 10.1034/j.1600‐051x.2002.290502.x 10.1080/00016350500469680 10.1902/jop.1988.59.5.318 10.1111/iej.12849 10.3389/fendo.2020.00484 10.1007/s11626‐019‐00426‐4 10.3389/fimmu.2018.01804 10.1902/jop.2007.060149 10.1177/154405910608500406 10.1007/s00784‐012‐0893‐z 10.1038/nri3073 10.1902/jop.2003.74.10.1454 10.1016/j.imbio.2005.05.010 10.1111/iej.13316 10.1902/jop.2003.74.10.1475 10.1111/j.1600‐051X.2005.00786.x 10.6061/clinics/2017(12)11 10.1016/j.joen.2016.01.022 10.3390/ijms18020440 10.1177/00220345960750021001 10.1007/s00266‐019‐01327‐3 10.1111/iej.13014 10.1902/jop.2002.73.9.982 |
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| References_xml | – volume: 29 start-page: 384 issue: 5 year: 2002 end-page: 391 article-title: Granulocyte elastase, matrix metalloproteinase‐8 and prostaglandin E2 in gingival crevicular fluid in matched clinical sites in smokers and non‐smokers with persistent periodontitis publication-title: Journal of Clinical Periodontology – volume: 112 start-page: 115 issue: 2 year: 2004 end-page: 120 article-title: Tobacco smoking and dental periapical condition publication-title: European Journal of Oral Sciences – volume: 16 start-page: 1 issue: 1 year: 2000 end-page: 8 article-title: Macrophages in periapical lesions publication-title: Endodontics & Dental Traumatology – volume: 73 start-page: 982 issue: 9 year: 2002 end-page: 987 article-title: Intermittent cigarette smoke inhalation may affect bone volume around titanium implants in rats publication-title: Journal of Periodontology – volume: 18 start-page: 40 issue: 1 year: 2017 article-title: Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity publication-title: Respiratory Research – volume: 53 start-page: 627 issue: 5 year: 2020 end-page: 635 article-title: Immunophenotypic quantification of M1 and M2 macrophage polarization in radicular cysts of primary and permanent teeth publication-title: International Endodontic Journal – volume: 31 start-page: 52 issue: 1 year: 2019 end-page: 57 article-title: Comparative analysis of prevalence of apical periodontitis in smokers and non‐smokers using cone‐beam computed tomography publication-title: The Saudi Dental Journal – volume: 74 start-page: 1475 issue: 10 year: 2003 end-page: 1482 article-title: Effect of tobacco smoking on neutrophil activity following periodontal surgery publication-title: Journal of Periodontology – volume: 7 start-page: 117 issue: 3 year: 1981 end-page: 122 article-title: Quantitative analysis of cellular composition of human periapical granuloma publication-title: Journal of Endodontics – volume: 87 start-page: 1155 issue: 12 year: 2008 end-page: 1159 article-title: iNOS‐derived nitric oxide modulates infection‐stimulated bone loss publication-title: Journal of Dental Research – volume: 6 start-page: 212 year: 2015 article-title: Anatomy of a discovery: m1 and m2 macrophages publication-title: Frontiers in Immunology – volume: 11 start-page: 723 issue: 11 year: 2011 end-page: 737 article-title: Protective and pathogenic functions of macrophage subsets publication-title: Nature Reviews. Immunology – volume: 77 start-page: 599 issue: 4 year: 2006 end-page: 605 article-title: Effect of cigarette smoke inhalation and estrogen deficiency on bone healing around titanium implants: a histometric study in rats publication-title: Journal of Periodontology – volume: 42 start-page: 747 issue: 5 year: 2016 end-page: 751 article-title: Multiple apical periodontitis influences serum levels of cytokines and nitric oxide publication-title: Journal of Endodontics – volume: 15 issue: 8 year: 2020 article-title: Chronic consumption of alcohol increases alveolar bone loss publication-title: PLoS One – volume: 71 start-page: 58 issue: 1 year: 2000 end-page: 62 article-title: Effect of cigarette smoking on oral elastase activity in adult periodontitis patients publication-title: Journal of Periodontology – volume: 131 year: 2021 article-title: Lack of 5‐ lipoxygenase in intramembranous and endochondral 129Sv mice skeleton and intramembranous healing publication-title: Archives of Oral Biology – volume: 44 start-page: 604 issue: 4 year: 2018 end-page: 608 article-title: Omega‐3 fatty acids reduce inflammation in rat apical periodontitis publication-title: Journal of Endodontics – volume: 78 start-page: 527 issue: 3 year: 2007 end-page: 532 article-title: A histologic and histometric assessment of the influence of nicotine on alveolar bone loss in rats publication-title: Journal of Periodontology – volume: 25 start-page: 677 issue: 12 year: 2004 end-page: 686 article-title: The chemokine system in diverse forms of macrophage activation and polarization publication-title: Trends in Immunology – volume: 33 year: 2019 article-title: Macrophages subpopulations in chronic periapical lesions according to clinical and morphological aspects publication-title: Brazilian Oral Research – volume: 64 start-page: 123 issue: 2 year: 2006 end-page: 128 article-title: Socio‐economic risk indicators for apical periodontitis publication-title: Acta Odontologica Scandinavica – volume: 54 start-page: 2276 issue: 12 year: 2021 end-page: 2289 article-title: Effect of red wine or its polyphenols on induced apical periodontitis in rats publication-title: International Endodontic Journal – volume: 75 start-page: 796 issue: 2 year: 1996 end-page: 802 article-title: Serum cotinine levels, smoking, and periodontal attachment loss publication-title: Journal of Dental Research – volume: 24 start-page: 4571 issue: 12 year: 2020 end-page: 4581 article-title: Macrophages skew towards M1 profile through reduced CD163 expression in symptomatic apical periodontitis publication-title: Clinical Oral Investigations – volume: 54 start-page: 1353 issue: 8 year: 2021 end-page: 1361 article-title: Inflammatory profile of apical periodontitis associated with liver fibrosis in rats: histological and immunohistochemical analysis publication-title: International Endodontic Journal – volume: 74 start-page: 1454 issue: 10 year: 2003 end-page: 1459 article-title: A comparative study on the effect of nicotine administration and cigarette smoke inhalation on bone healing around titanium implants publication-title: Journal of Periodontology – volume: 52 start-page: 329 issue: 3 year: 2019 end-page: 336 article-title: Chronic alcohol consumption increases inflammation and osteoclastogenesis in apical periodontitis publication-title: International Endodontic Journal – volume: 32 issue: Suppl 1 year: 2018 article-title: Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials publication-title: Brazilian Oral Research – volume: 22 start-page: 385 issue: 1 year: 2018 end-page: 394 article-title: Macrophage polarization differs between apical granulomas, radicular cysts, and dentigerous cysts publication-title: Clinical Oral Investigations – volume: 107 year: 2020 article-title: Inflammatory response and macrophage polarization using different physicochemical biomaterials for oral and maxillofacial reconstruction publication-title: Materials Science & Engineering. C, Materials for Biological Applications – volume: 78 start-page: 533 issue: 3 year: 2007 end-page: 541 article-title: Nicotine and lipopolysaccharide affect cytokine expression from gingival fibroblasts publication-title: Journal of Periodontology – volume: 14 start-page: 281 issue: 3 year: 2019 end-page: 287 article-title: Macrophage phenotypes and Gas6/Axl signaling in apical lesions publication-title: Journal of Dental Sciences – volume: 46 start-page: 959 issue: 8 year: 2002 end-page: 964 article-title: Immune response in asymptomatic smokers publication-title: Acta Anaesthesiologica Scandinavica – volume: 210 start-page: 153 issue: 2–4 year: 2005 end-page: 160 article-title: The macrophage scavenger receptor CD163 publication-title: Immunobiology – volume: 136 start-page: 1047 issue: 5 year: 2004 end-page: 1053 article-title: Effect of smoking and abstention on oxidative burst and reactivity of neutrophils and monocytes publication-title: Surgery – volume: 98 start-page: 200 issue: 2 year: 2019 end-page: 208 article-title: Induction of M2 macrophages prevents bone loss in murine periodontitis models publication-title: Journal of Dental Research – volume: 21 start-page: 2613 issue: 8 year: 2017 end-page: 2618 article-title: Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin publication-title: Clinical Oral Investigations – volume: 10 issue: 3 year: 2021 article-title: A mouse model for studying the development of apical periodontitis with age publication-title: Cell – volume: 30 start-page: 187 issue: 4 year: 2000 end-page: 190 article-title: Cigarette smoking as an aggravating factor in inflammatory tissue‐destructive diseases. Increase in tumor necrosis Factor‐ alpha priming of peripheral neutrophils measured as generation of oxygen radicals publication-title: International Journal of Clinical & Laboratory Research – volume: 45 start-page: 583 issue: 4 year: 2010 end-page: 588 article-title: Interleukin‐1 and interleukin‐8 in nicotine‐ and lipopolysaccharide‐exposed gingival keratinocyte cultures publication-title: Journal of Periodontal Research – volume: 17 start-page: 1947 issue: 8 year: 2013 end-page: 1955 article-title: Is smoking a predictor of apical periodontitis? publication-title: Clinical Oral Investigations – volume: 56 start-page: 465 issue: 4 year: 2023 end-page: 474 article-title: Inflammatory profile of apical periodontitis exacerbated by cigarette smoke inhalation: histological and immunohistochemical analysis in rats publication-title: International Endodontic Journal – volume: 43 start-page: 815 issue: 3 year: 2019 end-page: 825 article-title: Effects of cigarette smoke on fat graft survival in an experimental rat model publication-title: Aesthetic Plastic Surgery – volume: 47 start-page: 755 issue: 5 year: 2021 end-page: 761 article-title: Immunoexpression of interleukin 17, 6, and 1 Beta in primary chronic apical periodontitis in smokers and nonsmokers publication-title: Journal of Endodontics – volume: 17 start-page: 1155 issue: 4 year: 2013 end-page: 1164 article-title: Nicotine effect on inflammatory and growth factor responses in murine cutaneous wound healing publication-title: International Immunopharmacology – volume: 9 year: 2018 article-title: CCR2 contributes to F4/80+ cells migration along intramembranous bone healing in maxilla, but its deficiency does not critically affect the healing outcome publication-title: Frontiers in Immunology – volume: 85 start-page: 313 issue: 4 year: 2006 end-page: 317 article-title: Cigarette smoking increases the risk of root canal treatment publication-title: Journal of Dental Research – volume: 59 start-page: 318 issue: 5 year: 1988 end-page: 325 article-title: The effect of nicotine on the attachment of human fibroblasts to glass and human root surfaces in vitro publication-title: Journal of Periodontology – volume: 90 start-page: 95 issue: 1 year: 2000 end-page: 101 article-title: Apical periodontitis and related factors in an adult Lithuanian population publication-title: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics – volume: 53 start-page: 676 issue: 5 year: 2015 end-page: 688 article-title: Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages publication-title: American Journal of Respiratory Cell and Molecular Biology – volume: 53 start-page: 924 issue: 5 year: 2018 end-page: 931 article-title: Effect of orthodontic force associated with cigarette smoke inhalation in healthy and diseased periodontium. A histometric and immunohistochemistry analysis in rats publication-title: Journal of Periodontal Research – volume: 18 issue: 2 year: 2017 article-title: Matrix metalloproteinases as regulators of periodontal inflammation publication-title: International Journal of Molecular Sciences – volume: 72 start-page: 785 issue: 12 year: 2017 end-page: 789 article-title: Second hand tobacco smoke adversely affects the bone of immature rats publication-title: Clinics (São Paulo, Brazil) – volume: 38 start-page: 584 issue: 5 year: 2012 end-page: 588 article-title: Tobacco smoking and radiographic periapical status: a retrospective case‐control study publication-title: Journal of Endodontics – volume: 54 start-page: 848 issue: 6 year: 2021 end-page: 857 article-title: PRIASE 2021 guidelines for reporting animal studies in Endodontology: a consensus‐based development publication-title: International Endodontic Journal – volume: 37 start-page: 764 issue: 6 year: 2011 end-page: 767 article-title: Relationship between smoking and endodontic variables in hypertensive patients publication-title: Journal of Endodontics – volume: 32 start-page: 180 issue: Suppl 6 year: 2005 end-page: 195 article-title: Mechanisms of action of environmental factors–tobacco smoking publication-title: Journal of Clinical Periodontology – volume: 51 start-page: e87 issue: Suppl 2 year: 2018 end-page: e93 article-title: M2 macrophages coexist with a Th1‐driven profile in periapical cysts publication-title: International Endodontic Journal – volume: 53 start-page: 1068 issue: 8 year: 2020 end-page: 1083 article-title: Does tobacco smoking predispose to apical periodontitis and endodontic treatment need? A systematic review and meta‐analysis publication-title: International Endodontic Journal – volume: 22 start-page: 336 issue: 4 year: 2014 end-page: 346 article-title: Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status publication-title: Journal of Applied Oral Science: Revista FOB – volume: 33 start-page: 399 issue: 4 year: 2007 end-page: 402 article-title: Factors affecting outcomes for single‐tooth implants and endodontic restorations publication-title: Journal of Endodontics – volume: 475 start-page: 894 issue: 3 year: 2017 end-page: 902 article-title: Exposure to secondhand smoke impairs fracture healing in rats publication-title: Clinical Orthopaedics and Related Research – volume: 11 year: 2020 article-title: New surgical model for bone‐muscle injury reveals age and gender‐related healing patterns in the 5 lipoxygenase (5LO) knockout mouse publication-title: Frontiers in Endocrinology – volume: 31 start-page: 59 issue: 1 year: 2003 end-page: 67 article-title: Risk indicators for apical periodontitis publication-title: Community Dentistry and Oral Epidemiology – volume: 90 start-page: 1164 issue: 10 year: 2011 end-page: 1170 article-title: Host‐pathogen interactions in progressive chronic periodontitis publication-title: Journal of Dental Research – volume: 22 start-page: 311 issue: 6 year: 1996 end-page: 316 article-title: Kinetics of macrophages and lymphoid cells during the development of experimentally induced periapical lesions in rat molars: a quantitative immunohistochemical study publication-title: Journal of Endodontics – volume: 40 start-page: 290 issue: 4 year: 2007 end-page: 299 article-title: Risk factors for developing apical periodontitis in a general population publication-title: International Endodontic Journal – volume: 56 start-page: 154 issue: 2 year: 2020 end-page: 164 article-title: Effect of CSE on M1/M2 polarization in alveolar and peritoneal macrophages at different concentrations and exposure in vitro publication-title: In Vitro Cellular & Developmental Biology: Animal – ident: e_1_2_10_41_1 doi: 10.1016/j.it.2004.09.015 – ident: e_1_2_10_61_1 doi: 10.1016/j.surg.2004.04.001 – ident: e_1_2_10_62_1 doi: 10.1016/S0099‐2399(81)80125‐2 – ident: e_1_2_10_69_1 doi: 10.1034/j.1399‐6576.2002.460806.x – ident: e_1_2_10_33_1 doi: 10.1007/s005990070005 – ident: e_1_2_10_5_1 doi: 10.1016/j.joen.2017.12.008 – ident: e_1_2_10_3_1 doi: 10.1902/jop.2007.060296 – ident: e_1_2_10_8_1 doi: 10.1111/j.1600‐0722.2004.00112.x – ident: e_1_2_10_44_1 doi: 10.1016/j.msec.2019.110229 – ident: e_1_2_10_57_1 doi: 10.1007/s11999‐016‐5184‐6 – ident: e_1_2_10_26_1 doi: 10.1111/jre.12584 – ident: e_1_2_10_35_1 doi: 10.1111/j.1600‐0765.2009.01262.x – ident: e_1_2_10_67_1 doi: 10.1007/s00784‐017‐2123‐1 – ident: e_1_2_10_70_1 doi: 10.1177/0022034518805984 – ident: e_1_2_10_16_1 doi: 10.1016/j.jds.2018.12.002 – ident: e_1_2_10_18_1 doi: 10.1590/1807‐3107bor‐2018.vol32.0068 – ident: e_1_2_10_22_1 doi: 10.1016/j.joen.2006.12.025 – ident: e_1_2_10_31_1 doi: 10.3390/cells10030671 – ident: e_1_2_10_43_1 doi: 10.3389/fimmu.2015.00212 – ident: e_1_2_10_2_1 doi: 10.1067/moe.2000.107059 – ident: e_1_2_10_21_1 doi: 10.1371/journal.pone.0232731 – ident: e_1_2_10_59_1 doi: 10.1016/j.archoralbio.2021.105266 – ident: e_1_2_10_30_1 doi: 10.1177/154405910808701207 – ident: e_1_2_10_56_1 doi: 10.1007/s00784‐017‐2062‐x – ident: e_1_2_10_6_1 doi: 10.1016/j.sdentj.2018.09.006 – ident: e_1_2_10_38_1 doi: 10.1034/j.1600‐0528.2003.00032.x – ident: e_1_2_10_14_1 doi: 10.1902/jop.2006.050190 – ident: e_1_2_10_64_1 doi: 10.1016/j.joen.2021.01.010 – ident: e_1_2_10_65_1 doi: 10.1111/iej.13883 – ident: e_1_2_10_19_1 doi: 10.1111/iej.13633 – ident: e_1_2_10_13_1 doi: 10.1111/iej.13519 – ident: e_1_2_10_66_1 doi: 10.1007/s00784‐020‐03324‐2 – ident: e_1_2_10_68_1 doi: 10.1016/j.intimp.2013.10.022 – ident: e_1_2_10_49_1 doi: 10.1902/jop.2000.71.1.58 – ident: e_1_2_10_58_1 doi: 10.1016/j.joen.2011.03.004 – ident: e_1_2_10_9_1 doi: 10.1111/iej.13257 – ident: e_1_2_10_27_1 doi: 10.1590/1807‐3107bor‐2019.vol33.0047 – ident: e_1_2_10_63_1 doi: 10.1165/rcmb.2015‐0012OC – ident: e_1_2_10_42_1 doi: 10.1034/j.1600‐9657.2000.016001001.x – ident: e_1_2_10_34_1 doi: 10.1177/0022034511401405 – ident: e_1_2_10_4_1 doi: 10.1590/1678‐775720140140 – ident: e_1_2_10_37_1 doi: 10.1111/j.1365‐2591.2007.01224.x – ident: e_1_2_10_36_1 doi: 10.1016/S0099‐2399(96)80266‐4 – ident: e_1_2_10_46_1 doi: 10.1111/iej.13477 – ident: e_1_2_10_7_1 doi: 10.1186/s12931‐017‐0522‐0 – ident: e_1_2_10_40_1 doi: 10.1016/j.joen.2012.02.011 – ident: e_1_2_10_60_1 doi: 10.1034/j.1600‐051x.2002.290502.x – ident: e_1_2_10_29_1 doi: 10.1080/00016350500469680 – ident: e_1_2_10_52_1 doi: 10.1902/jop.1988.59.5.318 – ident: e_1_2_10_53_1 doi: 10.1111/iej.12849 – ident: e_1_2_10_10_1 doi: 10.3389/fendo.2020.00484 – ident: e_1_2_10_25_1 doi: 10.1007/s11626‐019‐00426‐4 – ident: e_1_2_10_11_1 doi: 10.3389/fimmu.2018.01804 – ident: e_1_2_10_12_1 doi: 10.1902/jop.2007.060149 – ident: e_1_2_10_39_1 doi: 10.1177/154405910608500406 – ident: e_1_2_10_54_1 doi: 10.1007/s00784‐012‐0893‐z – ident: e_1_2_10_45_1 doi: 10.1038/nri3073 – ident: e_1_2_10_15_1 doi: 10.1902/jop.2003.74.10.1454 – ident: e_1_2_10_24_1 doi: 10.1016/j.imbio.2005.05.010 – ident: e_1_2_10_51_1 doi: 10.1111/iej.13316 – ident: e_1_2_10_50_1 doi: 10.1902/jop.2003.74.10.1475 – ident: e_1_2_10_48_1 doi: 10.1111/j.1600‐051X.2005.00786.x – ident: e_1_2_10_55_1 doi: 10.6061/clinics/2017(12)11 – ident: e_1_2_10_17_1 doi: 10.1016/j.joen.2016.01.022 – ident: e_1_2_10_28_1 doi: 10.3390/ijms18020440 – ident: e_1_2_10_32_1 doi: 10.1177/00220345960750021001 – ident: e_1_2_10_23_1 doi: 10.1007/s00266‐019‐01327‐3 – ident: e_1_2_10_20_1 doi: 10.1111/iej.13014 – ident: e_1_2_10_47_1 doi: 10.1902/jop.2002.73.9.982 |
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To evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats.
Methodology
In... ObjectiveTo evaluate the effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats.MethodologyIn... OBJECTIVETo evaluate the effects of cigarette smoke inhalation on the immune-inflammatory profile of experimental apical periodontitis in rats.METHODOLOGYIn... |
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| SubjectTerms | animal model Animal models Cigarette smoke Cigarettes Gum disease Inflammation Inhalation macrophages Nitric-oxide synthase periapical periodontitis Periodontitis Smoke inhalation smokers Statistical analysis |
| Title | Effects of cigarette smoke inhalation on the immune‐inflammatory profile of experimental apical periodontitis in rats |
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