Astaxanthin, a carotenoid without vitamin A activity, augments antibody responses in cultures including T-helper cell clones and suboptimal doses of antigen

Astaxanthin, a carotenoid without vitamin A activity, enhances T-dependent antigen (Ag)-specific humoral immune responses. We examined carotenoid actions on T-helper (Th) cell activity in a direct manner with reconstitution experiments; spleen Th cells were replaced with Ag-specific Type 1 and Type...

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Bibliographic Details
Published in:	The Journal of nutrition Vol. 125; no. 10; p. 2483
Main Authors:	Jyonouchi, H, Sun, S, Tomita, Y, Gross, M D
Format:	Journal Article
Language:	English
Published:	United States 01-10-1995
Subjects:	Animals Antigens - immunology B-Lymphocytes - cytology B-Lymphocytes - drug effects B-Lymphocytes - immunology beta Carotene Carotenoids - pharmacology Cells, Cultured Clone Cells Columbidae Cytochrome c Group - immunology Dose-Response Relationship, Drug Enzyme-Linked Immunosorbent Assay Female gamma-Globulins - immunology Immunoglobulin G - biosynthesis Immunoglobulin M - biosynthesis Immunoglobulins - biosynthesis Mice Mice, Inbred DBA Rabbits Spleen - cytology T-Lymphocytes, Helper-Inducer - cytology T-Lymphocytes, Helper-Inducer - drug effects T-Lymphocytes, Helper-Inducer - immunology Vitamin A - physiology Xanthophylls
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