Mechanisms of dexamethasone-induced insulin resistance in healthy humans

Insulin resistance may result from decreased muscle blood flow, impaired cellular glucose transport, or intracellular deficits of glucose metabolism. The mechanisms responsible for dexamethasone-induced insulin resistance were investigated in healthy human subjects. During a 2-h hyperinsulinemic cla...

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Bibliographic Details

Published in:	The journal of clinical endocrinology and metabolism Vol. 79; no. 4; p. 1063
Main Authors:	Tappy, L, Randin, D, Vollenweider, P, Vollenweider, L, Paquot, N, Scherrer, U, Schneiter, P, Nicod, P, Jéquier, E
Format:	Journal Article
Language:	English
Published:	United States 01-10-1994
Subjects:	Adult Blood Glucose - analysis Dexamethasone - pharmacology Female Glucose - metabolism Glucose Clamp Technique Humans Hypolipidemic Agents - pharmacology Insulin - blood Insulin Resistance Leg - blood supply Male Oxidation-Reduction - drug effects Pyrazines - pharmacology Regional Blood Flow - drug effects
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