POLKADOTS Are Foci of Functional Interactions in T-Cell Receptor–mediated Signaling to NF-κB

Stimulation of the T-cell receptor (TCR) results in the activation of several transcription factors, including NF-κB, that are crucial for T-cell proliferation and gain of effector functions. On TCR engagement, several proteins within the TCR-directed NF-κB signaling pathway undergo dynamic spatial...

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Bibliographic Details
Published in:Molecular biology of the cell Vol. 17; no. 5; pp. 2166 - 2176
Main Authors: Rossman, Jeremy S., Stoicheva, Natalia G., Langel, Felicia D., Patterson, George H., Lippincott-Schwartz, Jennifer, Schaefer, Brian C.
Format: Journal Article
Language:English
Published: 01-05-2006
Online Access:Get full text
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