ANTIGENICITY TESTS OF TAZOBACTAM/PIPERACILLIN, TAZOBACTAM AND PIPERACILLIN

The antigenicity tests of Tazobactam/piperacillin (TAZ/PIPC), tazobactam (TAZ: β-lactamase inhibitor) and piperacillin (PIPC: penicillin antibiotic) were performed in mice and guinea pigs. The following results were obtained. 1. TAZ/PIPC, TAZ or PIPC had no immunogenicity and allergenicity in either...

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Bibliographic Details
Published in:	Journal of toxicological sciences Vol. 19; no. SupplementII; pp. 249 - 262
Main Authors:	TAKEMOTO, Minoru, MATSUO, Kouya, OGURO, Motoharu, KOUCHI, Yasuhide
Format:	Journal Article
Language:	English Japanese
Published:	Japan The Japanese Society of Toxicology 1994 Japan Science and Technology Agency
Subjects:	Animals Antigens - immunology beta-Lactamase Inhibitors Drug Therapy, Combination - immunology Female Guinea Pigs Humans Immunization Male Mice Mice, Inbred BALB C Mice, Inbred C3H Passive Cutaneous Anaphylaxis Penicillanic Acid - analogs & derivatives Penicillanic Acid - immunology Piperacillin - immunology Rats Rats, Sprague-Dawley Tazobactam
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