Evaluation of the Antiproliferative Potential of Yellow Jaboticaba (Myrciaria glazioviana) Extracts Against Human Cervical Cancer (HeLa cells line) and the Analysis of Their Chemical Composition by HPLC‐HRESIMS

Cervical cancer is a specific type of cancer that affects women around the world, with an incidence of 604 thousand new cases per year and 341 thousand deaths. There is a high demand for new effective antineoplastic drugs with few side effects. In this sense, recent research highlights the potential...

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Bibliographic Details
Published in:	Chemistry & biodiversity Vol. 21; no. 5; pp. e202301467 - n/a
Main Authors:	Toledo Martins Pereira, Mariana, Sardou Charret, Thiago, Freimann Wermelinger, Guilherme, Soares Ribeiro Nogueira, Thalya, Kaufmann Robbs, Bruno, Carvalho Castiglione, Raquel, Loureiro Simões, Rafael, Dantas Machado, Ricardo Luiz, Curcino Vieira, Ivo José, Abreu, Lucas Silva, D'Avila Bitencourt Pascoal, Vinicius, Rheder Fagundes Pascoal, Aislan Cristina
Format:	Journal Article
Language:	English
Published:	Switzerland Wiley Subscription Services, Inc 01-05-2024
Subjects:	Acetic acid Acids Animals Anticancer Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic drugs Antiproliferatives Antitumor activity Apoptosis Apoptosis - drug effects Bioactive compounds Cancer Cell death Cell migration Cell Proliferation - drug effects Cell Survival - drug effects Cervical Cervical cancer Chemical composition Chromatography, High Pressure Liquid Dichloromethane Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Ellagic acid Ethyl acetate Female HeLa Cells High-performance liquid chromatography Humans Indigenous species Inflammation Liquid chromatography Mice Myrciaria Myrtaceae Myrtaceae - chemistry Natural Products Phytochemistry Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Leaves - chemistry Quinic acid Side effects Spectrometry, Mass, Electrospray Ionization Tumor cells Tumors Uterine Cervical Neoplasms - drug therapy Uterine Cervical Neoplasms - pathology Myrtaceae Natural Products Anticancer Phytochemistry Cervical Cancer
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