Dopamine Receptors and TAAR1 Functional Interaction Patterns in the Duodenum Are Impaired in Gastrointestinal Disorders

Currently, there is a growing amount of evidence for the involvement of dopamine receptors and the functionally related trace amine-associated receptor, TAAR1, in upper intestinal function. In the present study, we analyzed their expression in the duodenum using publicly accessible transcriptomic da...

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Bibliographic Details
Published in:	Biomedicines Vol. 12; no. 7; p. 1590
Main Authors:	Vaganova, Anastasia N, Markina, Alisa A, Belousov, Aleksandr M, Lenskaia, Karina V, Gainetdinov, Raul R
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 17-07-2024
Subjects:	Antiemetics Datasets Diabetes mellitus diabetic gastroparesis Dopamine Dopamine D1 receptors Dopamine D2 receptors Dopamine D4 receptors Dopamine D5 receptors DRD2 DRD4 DRD5 Duodenum Dyspepsia Enteric nervous system functional dyspepsia Gastrointestinal diseases Gene expression Ligands Localization Neurons Permeability Receptor mechanisms Semantics Small intestine Statistical analysis TAAR1 Transcriptomics diabetic gastroparesis functional dyspepsia DRD2 trace amines TAAR1 dopamine DRD4 duodenum DRD5
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