Temporal trend in venous thromboembolism hospitalization rates in Brazilian older adults, 2010–2020

• Published in: Journal of thrombosis and thrombolysis Vol. 55; no. 1; pp. 156 - 165
• Main Authors: Barp, Milara, Carneiro, Viviane Santos Mendes, Malaquias, Suelen Gomes, Pagotto, Valéria
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-01-2023; Springer Nature B.V
• Subjects: Aged; Brazil - epidemiology; Cardiology; Confidence intervals; Diagnosis; Ecological studies; Hematology; Hospitalization; Humans; Medicine; Medicine & Public Health; Older people; Pulmonary Embolism - diagnosis; Pulmonary Embolism - epidemiology; Pulmonary Embolism - therapy; Pulmonary embolisms; Risk Factors; Thromboembolism; Thrombosis; Trends; Venous Thromboembolism - diagnosis; Venous Thromboembolism - epidemiology; Venous Thromboembolism - therapy; Venous Thrombosis - epidemiology; Venous Thrombosis - therapy; Brazil; Pulmonary embolism; Time series studies; Ecological studies; Aging; Venous thrombosis; Older adults; Epidemiology
• ISSN: 1573-742X; 0929-5305; 1573-742X
• DOI: 10.1007/s11239-022-02724-3

Aging is one of the main risk factors for venous thromboembolism (VTE). Changes in prevention, diagnosis, and treatment strategies for this condition in recent years require an analysis of its rates in health services. The objective of this study was to analyze a temporal trend of hospitalizations for VTE in Brazilian older adults. This ecological time series study used data from the Hospital Information System (HIS) on VTE hospitalizations from 2010 to 2020, selecting admissions with the main diagnosis of pulmonary thromboembolism (PTE) (I.26.0, I.26.9) and deep vein thrombosis (DVT) (I.80.0, I80.1, I80.2, I80.3, I80.8, I80.9). Hospitalization rates were calculated for each year and the Prais–Winsten. In Brazil, the trend of hospitalizations for VTE decreased, with an annual percentage change of – 40.71 (confidence interval [CI] – 50.46; − 29.04). DVT decreased, with an annual percentage change of − 43.14 (95% confidence interval [CI] − 51.36; − 33.54). All Brazilian regions showed a downward trend in hospitalizations for VTE and DVT, except for the Northeast region, which remained stable. Conversely, the trend of hospitalizations for PTE showed an upward in Brazil, with an annual percentage change of 4.33 (95% CI 1.26; 7.48). An upward trend was observed in hospitalizations for PTE in the Northeast region, and a stationary trend was observed in the other regions. The results showed a downward trend in hospitalization rates for DVT and an upward trend for PTE. The study indicates regional differences in rates and trends.