The importance of dermoscopy for the diagnosis of acquired bilateral telangiectatic macules: the angioid streak pattern reveals underlying chronic liver disease

• Published in: Journal of the European Academy of Dermatology and Venereology Vol. 32; no. 9; pp. 1597 - 1601
• Main Authors: Kim, G.‐W., Shin, K., Kim, T.‐W., You, H.‐S., Jin, H.‐J., Shim, W.‐H., Kim, H.‐S., Ko, H.‐C., Kim, B.‐S., Kim, M.‐B.
• Format: Journal Article
• Language: English
• Published: England 01-09-2018
• Subjects: Adult; Aged; Biomarkers; Chronic Disease; Dermoscopy; Female; Humans; Hyperpigmentation - complications; Hyperpigmentation - diagnostic imaging; Liver Diseases - complications; Liver Diseases - diagnosis; Male; Middle Aged; Severity of Illness Index; Telangiectasis - complications; Telangiectasis - diagnostic imaging
• ISSN: 0926-9959; 1468-3083
• DOI: 10.1111/jdv.14669

Background
Acquired bilateral telangiectatic macules (ABTM) are a newly recognized disease entity, which manifest as multiple telangiectatic pigmented macules confined mostly to the upper arms.
Objectives
To evaluate clinical and dermoscopic features in a group of 50 patients with ABTM and to determine the diagnostic usefulness of dermoscopy in ABTM.
Methods
Patients were selected from two tertiary teaching hospitals in Korea [Pusan National University Hospitals (Busan and Yangsan)]. Fifty patients (41 males and 9 females; mean age 48.1 years; range 26–78 years) with ABTM were included in the study. The dermoscopic findings were graded using a 4‐point scale: none (0), mild (1), moderate (2) and severe (3). In addition, the results of 23 patients with and 27 patients without chronic liver disease (CLD) were compared to determine whether the presence of CLD affects dermoscopic findings.
Results
Three distinct dermoscopic patterns were observed; brown pigmentations, telangiectasia (linear‐irregular vessels) and an angioid streak pattern. Brown pigmentation in the group without CLD had higher severity score than those in CLD group (mean score: 2.00 vs. 1.48, P = 0.033). However, mean telangiectasia severity score was higher in the CLD group (2.14 vs. 1.39, P < 0.001). The angioid streak pattern was more severe and more common in patients with CLD than in those without [1.37 vs. 0.35 (P < 0.001) and 63.0% vs. 26.1%, respectively].
Conclusions
Detailed observations with dermoscopy can provide first clues of the presence of ABTM and underlying chronic liver disease.