Re-Expression of Tafazzin Isoforms in TAZ-Deficient C6 Glioma Cells Restores Cardiolipin Composition but Not Proliferation Rate and Alterations in Gene Expression

Tafazzin—an acyltransferase—is involved in cardiolipin (CL) remodeling. CL is associated with mitochondrial function, structure and more recently with cell proliferation. Various tafazzin isoforms exist in humans. The role of these isoforms in cardiolipin remodeling is unknown. Aim of this study was...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 13; p. 931017
Main Authors:	Jagirdar, Gayatri, Elsner, Matthias, Scharf, Christian, Simm, Stefan, Borucki, Katrin, Peter, Daniela, Lalk, Michael, Methling, Karen, Linnebacher, Michael, Krohn, Mathias, Wolke, Carmen, Lendeckel, Uwe
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 25-07-2022
Subjects:	Barth syndrome Barth syndrome (BTHS) cardiolipin cellular proliferation gene expression Genetics tafazzin
Online Access:	Get full text
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