Malnutrition and Weight Loss as Prognostic Factors in the Survival of Patients with Gastric Cancer
There are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the association between nutritional status and three-year survival of patients with GC. In this prospective study, we included all histologically con...
Saved in:
| Published in: | Nutrition and cancer Vol. 74; no. 9; pp. 3140 - 3145 |
|---|---|
| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Taylor & Francis
13-08-2022
Taylor & Francis Ltd |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | There are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the association between nutritional status and three-year survival of patients with GC.
In this prospective study, we included all histologically confirmed GC patients admitted to the Imam Reza Hospital in Tabriz, Iran from September 2016 to October 2019. The nutritional status of patients was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA) form. All patients were followed up every six months for three years. The overall survival (OS) was calculated from the diagnosis date to the date of death or last visit.
In this study, 302 patients (mean age: 67.39 ± 12.04 years) with GC were included. The median OS was 11.00 mo, (95% CI: 80.03, 13.96). Only 28.4% of patients were well-nourished, and survived significantly longer than malnourished patients (20.5 vs. 8 mo, P = 0.01). The mortality hazard rate in patients with moderate and severe malnutrition was 2.04 times higher than well-nourished patients.
According to our results, the nutrition status of GC patients at the time of diagnosis was independently associated with their survival rate. |
|---|---|
| AbstractList | IntroductionThere are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the association between nutritional status and three-year survival of patients with GC.MethodsIn this prospective study, we included all histologically confirmed GC patients admitted to the Imam Reza Hospital in Tabriz, Iran from September 2016 to October 2019. The nutritional status of patients was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA) form. All patients were followed up every six months for three years. The overall survival (OS) was calculated from the diagnosis date to the date of death or last visit.ResultsIn this study, 302 patients (mean age: 67.39 ± 12.04 years) with GC were included. The median OS was 11.00 mo, (95% CI: 80.03, 13.96). Only 28.4% of patients were well-nourished, and survived significantly longer than malnourished patients (20.5 vs. 8 mo, P = 0.01). The mortality hazard rate in patients with moderate and severe malnutrition was 2.04 times higher than well-nourished patients.ConclusionAccording to our results, the nutrition status of GC patients at the time of diagnosis was independently associated with their survival rate. There are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the association between nutritional status and three-year survival of patients with GC. In this prospective study, we included all histologically confirmed GC patients admitted to the Imam Reza Hospital in Tabriz, Iran from September 2016 to October 2019. The nutritional status of patients was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA) form. All patients were followed up every six months for three years. The overall survival (OS) was calculated from the diagnosis date to the date of death or last visit. In this study, 302 patients (mean age: 67.39 ± 12.04 years) with GC were included. The median OS was 11.00 mo, (95% CI: 80.03, 13.96). Only 28.4% of patients were well-nourished, and survived significantly longer than malnourished patients (20.5 vs. 8 mo, P = 0.01). The mortality hazard rate in patients with moderate and severe malnutrition was 2.04 times higher than well-nourished patients. According to our results, the nutrition status of GC patients at the time of diagnosis was independently associated with their survival rate. There are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the association between nutritional status and three-year survival of patients with GC. In this prospective study, we included all histologically confirmed GC patients admitted to the Imam Reza Hospital in Tabriz, Iran from September 2016 to October 2019. The nutritional status of patients was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA) form. All patients were followed up every six months for three years. The overall survival (OS) was calculated from the diagnosis date to the date of death or last visit. In this study, 302 patients (mean age: 67.39 ± 12.04 years) with GC were included. The median OS was 11.00 mo, (95% CI: 80.03, 13.96). Only 28.4% of patients were well-nourished, and survived significantly longer than malnourished patients (20.5 vs. 8 mo, = 0.01). The mortality hazard rate in patients with moderate and severe malnutrition was 2.04 times higher than well-nourished patients. According to our results, the nutrition status of GC patients at the time of diagnosis was independently associated with their survival rate. |
| Author | Naghashi, Shahnaz Nikniaz, Zeinab Somi, Mohammad Hossein |
| Author_xml | – sequence: 1 givenname: Zeinab surname: Nikniaz fullname: Nikniaz, Zeinab organization: Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences – sequence: 2 givenname: Mohammad Hossein surname: Somi fullname: Somi, Mohammad Hossein organization: Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences – sequence: 3 givenname: Shahnaz surname: Naghashi fullname: Naghashi, Shahnaz organization: Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35373675$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUtLLDEQhYMoOo7-BC-Bu3HTmmcnvfMy-IIRBRWXId2dOJGeRJO04r83w4x34cJN1earU1Xn7INtH7wB4AijE4wkOkW4ppxLfEIQIaXwBslmC0wwp6QSDWbbYLJiqhW0B_ZTekEICUzlLtijnApaCz4B7Y0e_Jijyy54qH0Pn4x7XmQ4DylBneBdDM8-pOw6eKG7HGKCzsO8MPB-jO_uXQ8wWHinszM-J_jh8gJe6lQUOzjTvjPxAOxYPSRzuOlT8Hhx_jC7qua3l9ezf_Oqo4TlyhKLuprVwpKGSNtKxnpDaStarXvCkCU1FhZLxluMTctFi1n5tdZM1kJaQafgeK37GsPbaFJWS5c6MwzamzAmRYp4wyguz0_B3x_oSxijL9cpIhBlSBLBCsXXVBeLGdFY9RrdUsdPhZFahaC-Q1CrENQmhDL3Z6M-tkvT_5_6dr0AZ2vAeRviUn-EOPQq688hRBuLaS4p-vuOL1NGloY |
| CitedBy_id | crossref_primary_10_1080_16078454_2022_2078040 crossref_primary_10_1080_0284186X_2022_2114379 crossref_primary_10_3389_fnut_2023_1208375 crossref_primary_10_1017_S1368980024000788 crossref_primary_10_1155_2022_8263986 crossref_primary_10_1016_j_clnesp_2023_12_019 crossref_primary_10_1016_j_esmoop_2024_102241 crossref_primary_10_3390_nu16091363 crossref_primary_10_1186_s12893_024_02397_0 |
| Cites_doi | 10.2147/OTT.S140118 10.1017/S0007114518002854 10.1007/s12282-020-01067-2 10.1093/ajcn/73.2.323 10.1007/s00268-009-0140-1 10.1080/01635581.2019.1651347 10.1080/01635581.2017.1324996 10.1016/j.ejca.2014.01.029 10.1016/j.clnu.2005.05.001 10.1634/theoncologist.2009-0283 10.1097/MD.0000000000005024 10.1186/s12885-016-2934-5 10.1097/01.NCC.0000339247.60700.86 10.1016/j.it.2016.04.003 10.18632/oncotarget.5629 10.1177/014860718701100108 10.1016/j.ejso.2016.05.029 10.2147/OTT.S132432 10.1007/s00520-003-0568-z |
| ContentType | Journal Article |
| Copyright | 2022 Taylor & Francis Group, LLC 2022 2022 Taylor & Francis Group, LLC |
| Copyright_xml | – notice: 2022 Taylor & Francis Group, LLC 2022 – notice: 2022 Taylor & Francis Group, LLC |
| DBID | NPM AAYXX CITATION 7U7 C1K 7X8 |
| DOI | 10.1080/01635581.2022.2059089 |
| DatabaseName | PubMed CrossRef Toxicology Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitle | PubMed CrossRef Toxicology Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | Toxicology Abstracts MEDLINE - Academic PubMed |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Diet & Clinical Nutrition |
| EISSN | 1532-7914 |
| EndPage | 3145 |
| ExternalDocumentID | 10_1080_01635581_2022_2059089 35373675 2059089 |
| Genre | Articles Journal Article |
| GroupedDBID | --- .7I .QK 07V 0BK 0R~ 123 1PE 29N 36B 4.4 5RE 5VS 6PF AAGZJ AAJNR AALUX AAMIU AAPUL AAQRR AATTQ AAWTL ABBKH ABDBF ABEIZ ABLCE ABPEM ABPTK ABTAI ABUPF ABZLS ACENM ACGFS ACGOD ACKLR ACLSK ACPRK ACTOA ACVOX ADBBV ADCVX ADFCX AECIN AEKEX AEOZL AEPSL AEXWM AFOLD AFRAH AFWLO AGDLA AGFJD AGMYJ AGRBW AGYJP AIJEM AIRBT AJWEG AKBVH ALMA_UNASSIGNED_HOLDINGS ALQZU AMDAE ARJSQ AVBZW AWYRJ BLEHA BMOTO BMSDO BOHLJ BTKSN CCCUG CQ1 CS3 DGFLZ DKSSO EAL EAP EBS ECT ESX E~B E~C F5P FUNRP G-F GTTXZ H13 HF~ HZ~ IPNFZ J.O KDLKA KRBQP KSSTO KWAYT KYCEM LJTGL M4Z NA5 NZ~ O9- PQEST PQQKQ RIG RNANH RVRKI S-F STATR TFL TFW TNTFI UEQFS UT5 UT9 V1K VAE ~01 ~KM ~S~ 04C A8Z AAHBH ABJNI ABLIJ ABXYU ACIEZ ADOJX ALYBC EBB EBC EBD EBX ECF ECV EIHBH EMB EMK EMOBN ENC EPL EPT ESTFP NPM Q~Q SV3 TBQAZ TDBHL TERGH TUROJ TUS WQ9 AAYXX CITATION 7U7 C1K 7X8 |
| ID | FETCH-LOGICAL-c324t-f2f0c6467f2928fb844de33b7baad240f2617f1845b11eb57b145326a48678f73 |
| IEDL.DBID | TFW |
| ISSN | 0163-5581 |
| IngestDate | Sat Oct 26 00:25:44 EDT 2024 Thu Oct 10 22:20:54 EDT 2024 Fri Aug 23 00:38:38 EDT 2024 Wed Oct 16 00:42:36 EDT 2024 Tue Jun 13 19:52:41 EDT 2023 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 9 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c324t-f2f0c6467f2928fb844de33b7baad240f2617f1845b11eb57b145326a48678f73 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PMID | 35373675 |
| PQID | 2703408274 |
| PQPubID | 105635 |
| PageCount | 6 |
| ParticipantIDs | proquest_journals_2703408274 proquest_miscellaneous_2646943135 informaworld_taylorfrancis_310_1080_01635581_2022_2059089 pubmed_primary_35373675 crossref_primary_10_1080_01635581_2022_2059089 |
| PublicationCentury | 2000 |
| PublicationDate | 2022-08-13 |
| PublicationDateYYYYMMDD | 2022-08-13 |
| PublicationDate_xml | – month: 08 year: 2022 text: 2022-08-13 day: 13 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Mahwah |
| PublicationTitle | Nutrition and cancer |
| PublicationTitleAlternate | Nutr Cancer |
| PublicationYear | 2022 |
| Publisher | Taylor & Francis Taylor & Francis Ltd |
| Publisher_xml | – name: Taylor & Francis – name: Taylor & Francis Ltd |
| References | CIT0010 CIT0012 CIT0011 Hosseinnataj A (CIT0006) 2020; 13 Shahabbasi J (CIT0015) 2018; 9 CIT0014 CIT0013 Movahedi M (CIT0004) 2009; 14 CIT0016 CIT0018 Tchekmedyian N (CIT0021) 1992; 6 CIT0019 CIT0020 CIT0001 CIT0023 CIT0022 Andreoli A (CIT0017) 2011; 15 CIT0003 CIT0025 CIT0002 CIT0024 CIT0005 CIT0027 CIT0026 CIT0007 CIT0009 CIT0008 |
| References_xml | – volume: 6 start-page: 105 issue: 2 year: 1992 ident: CIT0021 publication-title: Oncology (Williston Park) contributor: fullname: Tchekmedyian N – ident: CIT0027 doi: 10.2147/OTT.S140118 – ident: CIT0024 doi: 10.1017/S0007114518002854 – ident: CIT0026 doi: 10.1007/s12282-020-01067-2 – ident: CIT0007 doi: 10.1093/ajcn/73.2.323 – ident: CIT0016 doi: 10.1007/s00268-009-0140-1 – volume: 13 start-page: 31 issue: 1 year: 2020 ident: CIT0006 publication-title: Gastroenterol Hepatol Bed Bench contributor: fullname: Hosseinnataj A – ident: CIT0013 doi: 10.1080/01635581.2019.1651347 – ident: CIT0010 doi: 10.1080/01635581.2017.1324996 – ident: CIT0002 doi: 10.1016/j.ejca.2014.01.029 – ident: CIT0020 doi: 10.1016/j.clnu.2005.05.001 – ident: CIT0019 doi: 10.1634/theoncologist.2009-0283 – volume: 15 start-page: 469 issue: 5 year: 2011 ident: CIT0017 publication-title: Eur Rev Med Pharmacol Sci contributor: fullname: Andreoli A – volume: 14 start-page: 367 issue: 6 year: 2009 ident: CIT0004 publication-title: J Res Med Sci contributor: fullname: Movahedi M – ident: CIT0025 doi: 10.1097/MD.0000000000005024 – ident: CIT0018 doi: 10.1186/s12885-016-2934-5 – ident: CIT0009 doi: 10.1097/01.NCC.0000339247.60700.86 – volume: 9 start-page: 149 year: 2018 ident: CIT0015 publication-title: Depic Health contributor: fullname: Shahabbasi J – ident: CIT0003 – ident: CIT0023 doi: 10.1016/j.it.2016.04.003 – ident: CIT0022 doi: 10.18632/oncotarget.5629 – ident: CIT0001 – ident: CIT0014 doi: 10.1177/014860718701100108 – ident: CIT0005 – ident: CIT0012 doi: 10.1016/j.ejso.2016.05.029 – ident: CIT0011 doi: 10.2147/OTT.S132432 – ident: CIT0008 doi: 10.1007/s00520-003-0568-z |
| SSID | ssj0007138 |
| Score | 2.4934082 |
| Snippet | There are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to assess the... IntroductionThere are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to... INTRODUCTIONThere are limited prospective studies assessing the post-diagnosis nutritional status of patients with gastric cancer (GC). This study aimed to... |
| SourceID | proquest crossref pubmed informaworld |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 3140 |
| SubjectTerms | Cancer Diagnosis Gastric cancer Malnutrition Medical prognosis Nutrition Nutritional status Patients Survival Weight loss |
| Title | Malnutrition and Weight Loss as Prognostic Factors in the Survival of Patients with Gastric Cancer |
| URI | https://www.tandfonline.com/doi/abs/10.1080/01635581.2022.2059089 https://www.ncbi.nlm.nih.gov/pubmed/35373675 https://www.proquest.com/docview/2703408274 https://search.proquest.com/docview/2646943135 |
| Volume | 74 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LS8NAEB58gHjxUV_RWkYQb9EmmzTJsdRGD7YIVfQWdpNdKJRUmvb_O5NH0YN40EsgJLvsY3b2m9mdbwCuU89JQ8P3dIJez_Zow7VVRg8hRSY5j7TucqDw4yQYv4f3Q6bJ6TexMHytkm1oUxFFlLqaF7dURXMj7o5QCpOCs3XnciwVp-3mED6HwABJ9Ev8ttbFZIKFFbu3sLlIE8PzUy3fdqdv3KU_I9ByJ4r3_6EPB7BXw1DsV3JzCBs6b4F1P9VLvMGaK3SG44aqvwU7o_oQ_gjUSM7y5gtSC_Ct9K_iE3UJZYHPizlf36OqMa7S-eA0R0KaOFmRZiLZxrnB54rRtUB2BeOD5AQiKQ5YChfH8BoPXwaPdp2qwU4JkS1t45pu2iOla9zIDY0KPS_TQqhASZkRaDBM_G7ImvSV42jlB4omi5CjZMK_0ATiBLbyea7PALVDe4FUWaBV6vVSwq9dX7oyynTmibQbWnDbTFHyUTFyJE5DdFqPasKjmtSjakH0dSKTZekKMVXekkT8UrbdzHpSL-4icUlLcp7uwLPgav2ZliWftchcz1f0Dw1GROBM-BacVtKybq3wRSDIUDv_Q8MuYJdf2bvtiDZsLRcrfQmbRbbqwHZ_MByPOuVK-ATHIwF1 |
| link.rule.ids | 315,783,787,1456,1510,27936,27937,58025,59738,59872,60527,60661 |
| linkProvider | Taylor & Francis |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LT8MwDLZ4SMCF96M8jYS4FdamXdsjgo0htgmJIbhFSZtISKhDe_x_7D4mdkAc4NJLmihxEuez43wGuEgDL40tx-lEzaYb0IHr6ow-QolMcR5p0-CHwp3nqP8W37WYJmf2FobDKtmGtiVRRKGreXOzM7oOibsmmMKs4Gze-fyYivN2J4uwTOBYcFjXoP0608ZkhMUlv7dwuU79iuenZubOpzn20p8xaHEWtTf-YxSbsF4hUbwpl84WLJh8G5y7dzPBS6zoQj-wX7P1b8NKr7qH3wHdUx95XYLUBXwtXKzYpTGhGuPTaMgRfNQ0tsuMPvieI4FNfJ6ScqLljUOLTyWp6xjZG4z3inOIpHjLC3G0Cy_t1uC241bZGtyUQNnEtb5tpE3Su9ZP_NjqOAgyI4SOtFIZ4QbL3O-WDMpQe57RYaS9ICTwqJjzL7aR2IOlfJibA0Dj0XGgdBYZnQbNlCBsI1S-SjKTBSJtxA5c1XMkP0tSDunVXKeVVCVLVVZSdSD5PpNyUnhDbJm6RIpf6h7X0y6r_T2WPilKTtUdBQ6cz4ppZ_J1i8rNcEr_kDASwmcidGC_XC6z3opQRIJstcM_dOwMVjuDXld2H_qPR7DGRezs9sQxLE1GU3MCi-Nselpshy_6AwQV |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1JT-wwDLZYJPQurO9BWY2EuPUxbdppe0QMBQSMRgIEtyhpEmkk1EGz_H_sLiM4IA5w6SVNlDiO_TnLZ4CTIgqK1PE9naTb9SNyuL429BFKGMV5pG2HHwpfPyT9l7R3yTQ55-1bGL5WyTG0q4kiKlvNi_vNuPZG3BmhFCYF5-gu5LdUnLY7W4TlOCUHTir9mD_PjTHFYGlN7y18rtM-4vmqmU_u6RN56dcQtHJF-dovDGIdVhsciue14mzAgi03wesN7RRPsSELfcV-y9W_CSv3zSn8Fuh79Vq2JUg9wOdqgxXvaEioJjgYj_j-HjWNeZ3PB4clEtTEhxmZJlJuHDkc1JSuE-S9YLxSnEGkwAtWw_FfeMovHy-u_SZXg18QJJv6LnSdoktW14VZmDqdRpGxQuhEK2UINThmfncUTsY6CKyOEx1EMUFHxYx_qUvEP1gqR6XdAbQBOQOlTWJ1EXULArCdWIUqM9ZEouikHvxvp0i-1ZQcMmiZThupSpaqbKTqQfZxIuW02gtxdeISKb6pu9_OumxW90SGZCY5UXcSeXA8L6Z1yYctqrSjGf1DwsgInYnYg-1aW-a9FbFIBEVquz_o2BGsDHq5vLvp3-7BHy7hne5A7MPSdDyzB7A4MbPDajG8A7LvArk |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Malnutrition+and+Weight+Loss+as+Prognostic+Factors+in+the+Survival+of+Patients+with+Gastric+Cancer&rft.jtitle=Nutrition+and+cancer&rft.au=Nikniaz%2C+Zeinab&rft.au=Somi%2C+Mohammad+Hossein&rft.au=Naghashi%2C+Shahnaz&rft.date=2022-08-13&rft.pub=Taylor+%26+Francis&rft.issn=0163-5581&rft.eissn=1532-7914&rft.volume=74&rft.issue=9&rft.spage=3140&rft.epage=3145&rft_id=info:doi/10.1080%2F01635581.2022.2059089&rft.externalDocID=2059089 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0163-5581&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0163-5581&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0163-5581&client=summon |