Why SLNB procedure is not currently used in early stage oral squamous cell carcinoma?

•SLNB is comparable to END in terms of Overall Survival in patients with early stage OSCC.•SLNB can provide a significant reduction in post-operative morbidity particularly in OSCC involving subsites such as the floor of the mouth.•99mTc-tilmanocept leads to identification rate for the floor of the...

Full description

Saved in:

Bibliographic Details
Published in:	Oral oncology Vol. 109; p. 104746
Main Authors:	Terenzi, Valentina, Follacchio, Giulia Anna, Cassoni, Andrea, Monteleone, Francesco, Nocini, Riccardo, Valentini, Valentino
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-10-2020
Subjects:	Elective neck dissection Oral squamous cell carcinoma Sentinel Lymph Node Biopsy Technetium-99m-radiolabeled colloid Sentinel Lymph Node Biopsy Elective neck dissection Oral squamous cell carcinoma Technetium-99m-radiolabeled colloid
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	•SLNB is comparable to END in terms of Overall Survival in patients with early stage OSCC.•SLNB can provide a significant reduction in post-operative morbidity particularly in OSCC involving subsites such as the floor of the mouth.•99mTc-tilmanocept leads to identification rate for the floor of the mouth subsite of 100%, with a 0% false-negative rate and high negative predictive value, reducing “shine-through” phenomenon.•SLNB in early stage OSCC patients is a reliable technique, to be performed preferentially in a multidisciplinary setting in trained centers
Bibliography:	SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2020.104746