5'-UTR-based phylogenetic analysis of Classical swine fever virus isolates from India

• Published in: Acta virologica (Anglickâa verze) Vol. 54; no. 1; p. 79
• Main Authors: Desai, G S, Sharma, A, Kataria, R S, Barman, N N, Tiwari, A K
• Format: Journal Article
• Language: English
• Published: Slovakia 2010
• Subjects: 5' Untranslated Regions - genetics; Animals; Classical Swine Fever - epidemiology; Classical Swine Fever - virology; Classical swine fever virus - classification; Classical swine fever virus - genetics; Classical swine fever virus - isolation & purification; DNA, Viral - analysis; Genotype; India - epidemiology; Molecular Sequence Data; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Swine - virology; India
• ISSN: 0001-723X
• DOI: 10.4149/av_2010_01_79

Classical swine fever (CSF) caused by Classical swine fever virus (CSFV) is a globally significant disease of pigs. Genetic typing of CSFV isolates can help in understanding the epidemiology of disease and trace down the source of outbreak. 5'-UTR sequence analysis and subsequent genetic classification of nine CSFV field isolates from India indicated that 3 isolates belonged to genotype 2.1 and were closely related to European CSFV strains. The remaining 6 isolates belonged to genotype 1 that contained old and new strains. However, the genotype 2.1 group consisted of recent field isolates only. The study showed circulation of both genotypes 1 and 2.1 in north-eastern part of India.