Bone marrow biopsy: RNA isolation with expression profiling in men with metastatic castration-resistant prostate cancer--factors affecting diagnostic success

To determine the rate at which computed tomographically guided pelvic percutaneous bone biopsy in men with metastatic castration-resistant prostate cancer (mCRPC) yields adequate tissue for genomic profiling and to identify issues likely to affect diagnostic yields. This study was institutional revi...

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Bibliographic Details
Published in:	Radiology Vol. 269; no. 3; pp. 816 - 823
Main Authors:	Spritzer, Charles E, Afonso, P Diana, Vinson, Emily N, Turnbull, James D, Morris, Karla K, Foye, Adam, Madden, John F, Roy Choudhury, Kingshuk, Febbo, Phillip G, George, Daniel J
Format:	Journal Article
Language:	English
Published:	United States Radiological Society of North America 01-12-2013
Subjects:	Biopsy Bone Density Conservation Agents - therapeutic use Bone Marrow - pathology Diphosphonates - therapeutic use Everolimus Gene Expression Profiling Humans Imidazoles - therapeutic use Immunosuppressive Agents - therapeutic use Male Original Research Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - drug therapy Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology RNA - isolation & purification Sirolimus - administration & dosage Sirolimus - analogs & derivatives Tomography, X-Ray Computed Ultrasonography, Interventional
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