Novel Coronavirus Infection in Febrile Infants Aged 60 Days and Younger

• Published in: Pediatrics (Evanston) Vol. 146; no. 3; p. 1
• Main Authors: McLaren, Son H, Dayan, Peter S, Fenster, Daniel B, Ochs, Julie B, Vindas, Marc T, Bugaighis, Mona N, Gonzalez, Ariana E, Lubell, Tamar R
• Format: Journal Article
• Language: English
• Published: United States American Academy of Pediatrics 01-09-2020
• Subjects: Age Factors; Antibiotics; Clinical Laboratory Techniques - methods; Coronaviridae; Coronavirus Infections - diagnosis; Coronavirus Infections - epidemiology; Coronaviruses; COVID-19; COVID-19 Testing; Diagnosis, Differential; Emergency Service, Hospital - statistics & numerical data; Female; Fever of Unknown Origin - diagnosis; Fever of Unknown Origin - etiology; Follow-Up Studies; Hospitals, Pediatric; Humans; Incidence; Infant; Infant, Newborn; Infants; Infections; Male; Mechanical ventilation; Pandemics; Pediatrics; Pneumonia, Viral - diagnosis; Pneumonia, Viral - epidemiology; Prospective Studies; Respiratory Tract Infections - complications; Respiratory Tract Infections - diagnosis; Retrospective Studies; Risk Assessment; Severe acute respiratory syndrome; Severe Acute Respiratory Syndrome - diagnosis; Severe Acute Respiratory Syndrome - epidemiology; Severe acute respiratory syndrome coronavirus 2; Urinary tract; Urinary Tract Infections - complications; Urinary Tract Infections - diagnosis
• ISSN: 0031-4005; 1098-4275
• DOI: 10.1542/peds.2020-1550

In this case series, we describe the clinical course and outcomes of 7 febrile infants aged ≤60 days with confirmed severe acute respiratory syndrome coronavirus 2 infection. No infant had severe outcomes, including the need for mechanical ventilation or ICU level of care. Two infants had concurrent urinary tract infections, which were treated with antibiotics. Although a small sample, our data suggest that febrile infants with severe acute respiratory syndrome coronavirus 2 infection often have mild illness.