Spontaneous liver rupture in hypereosinophilic syndrome： A rare but fatal complication

• Published in: World journal of gastroenterology : WJG Vol. 15; no. 46; pp. 5875 - 5878
• Main Authors: Cheung, Yue-Sun, Wong, Shun, Lam, Philip Koon-Ngai, Lee, Kit-Fai, Wong, John, Lai, Paul Bo-San
• Format: Journal Article
• Language: English
• Published: United States Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China%Department of Pathology, Princess Margaret Hospital, Hong Kong, China%Department of Anesthesia and Intensive Care, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China 14-12-2009; The WJG Press and Baishideng
• Subjects: Case Report; Fatal Outcome; Humans; Hypereosinophilic Syndrome - complications; Hypereosinophilic Syndrome - diagnosis; Hypereosinophilic Syndrome - pathology; Liver - pathology; Male; Middle Aged; Rupture, Spontaneous - diagnosis; Rupture, Spontaneous - etiology; Rupture, Spontaneous - mortality; 嗜酸细胞; 增多症; 并发症; 统计调查; Spontaneous liver rupture; Complication; Hemoperitoneum; Eosinophilia; Hypereosinophilic syndrome
• ISSN: 1007-9327; 2219-2840
• DOI: 10.3748/wjg.15.5875

We report a rare case of spontaneous liver rupture in a patient with hypereosinophilic syndrome （HES）, of which the diagnosis was delayed, resulting in a fatal outcome. The diagnostic criteria and treatment of HES with hepatic involvement were reviewed. The possible cause of spontaneous liver rupture in HES and its management were also discussed. To our knowledge, this is the first case report of spontaneous liver rupture in HES. We emphasized the need of a high index of suspicion in diagnosing HES, so that early treatment could be initiated.