Comparison of enoximone, amrinone, or levosimendan enriched St. Thomas' hospital cardioplegic solutions used for myocardial preservation in isolated guinea pig hearts

Myocardial contractile function after cardioplegic arrest is often depressed and an ideal cardioplegic solution has not been developed yet. The aim of this study was to assess the efficacy of phosphodiesterase III inhibitors, amrinone and enoximone, and levosimendan, a novel Ca2+ sensitizing agent,...

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Bibliographic Details
Published in:	Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove Vol. 45; no. 3; pp. 93 - 97
Main Authors:	Köksal, Cengiz, Süzer, Oner, Bozkurt, A Kürsat, Köseoğlu, Sebahat
Format:	Journal Article
Language:	English
Published:	Czech Republic Karolinum Press 2002
Subjects:	Amrinone Amrinone - administration & dosage Amrinone - pharmacology Animals Bicarbonates - administration & dosage Calcium Chloride - administration & dosage Cardioplegic Solutions - administration & dosage Cardiotonic Agents - administration & dosage Cardiotonic Agents - pharmacology Enoximone Enoximone - administration & dosage Enoximone - pharmacology Female Guinea Pigs Heart - drug effects Heart - physiology Heart Arrest, Induced Hydrazones - administration & dosage Hydrazones - pharmacology In Vitro Techniques Ischemia-reperfusion Levosimendan Magnesium - administration & dosage Male Myocardial Contraction Myocardial Reperfusion Injury - prevention & control Myocardium - metabolism Organ Preservation Phosphodiesterase Inhibitors - administration & dosage Phosphodiesterase Inhibitors - pharmacology Potassium Chloride - administration & dosage Pyridazines - administration & dosage Pyridazines - pharmacology Sodium Chloride - administration & dosage St. Thomas hospital cardioplegic solution
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