Fatal disseminated infection by Gymnascella hyalinospora in a heart transplant recipient

• Published in: Transplant infectious disease Vol. 21; no. 5; pp. e13128 - n/a
• Main Authors: Agnelli, Caroline, Valerio, Maricela, Olmedo, María, Guinea, Jesús, Zatarain‐Nicolás, Eduardo, del Carmen Martínez‐Jiménez, María, Alcalá, Luis, Escribano, Pilar, Cebollero Presmanes, María, Bouza, Emilio, Muñoz, Patricia, Martín‐Rabadán, Pablo
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01-10-2019
• Subjects: Adult; Antimicrobial agents; antimicrobial stewardship; Ascomycota - pathogenicity; Diagnostic systems; Disseminated infection; Fatal Outcome; Female; Heart transplantation; Heart Transplantation - adverse effects; Hospitals; Humans; Immunocompromised Host; Immunocompromised hosts; Infections; invasive fungal infections; Invasive Fungal Infections - diagnosis; Invasive Fungal Infections - etiology; Mycoses - diagnosis; Nosocomial infection; Opportunistic Infections - microbiology; Tomography, X-Ray Computed; Transplant Recipients; Virulence; antimicrobial stewardship; invasive fungal infections; heart transplantation; immunocompromised host
• ISSN: 1398-2273; 1399-3062
• DOI: 10.1111/tid.13128

We report the first case of disseminated infection by Gymnascella hyalinospora in a solid organ transplant recipient. This case highlights the role of low‐virulence environmental molds as an emerging cause of breakthrough invasive fungal infection in immunocompromised hosts. Nosocomial strategies of infection control including antimicrobial stewardship and advances on fast diagnostic methods are strongly encouraged to improve patient prognosis.