Effects of high- and moderate-intensity resistance training sessions on glycemia of insulin-treated and non-insulin-treated type 2 diabetes mellitus individuals

• Published in: Sport sciences for health Vol. 19; no. 2; pp. 625 - 636
• Main Authors: Ogando, Pedro H. M., Silveira-Rodrigues, João G., Melo, Bruno P., Campos, Bruno T., Silva, Anderson D. C., Barbosa, Ester G., Aleixo, Ivana M. S., Soares, Danusa D.
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01-06-2023; Springer Nature B.V
• Subjects: Aerobics; Diabetes; Drug therapy; Exercise intensity; Fitness training programs; Glucose; Human Physiology; Hyperglycemia; Insulin resistance; Kinases; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolism; Muscle contraction; Muscle strength; Original Article; Physical fitness; Pilot projects; Proteins; Sports Medicine; Strength training; Brazil; Strength training; Chronic disease; Metabolic health; Physical Therapy
• ISSN: 1824-7490; 1825-1234
• DOI: 10.1007/s11332-022-00931-2

Purpose
The objective was to analyze the capillary glucose (CG) responses of two resistance exercise intensities in type 2 diabetes mellitus (T2DM) individuals undergoing different drug therapies.
Methods
Twelve non-insulin treated (NIT), and six insulin-treated (IT) T2DM individuals (67 ± 7 years) performed two resistance-training sessions (RT-session) at moderate-intensity (MOD, 3 × 10 reps at 70% of 10-RM), high-intensity (HIGH, 3 × 10 reps at 100% of 10-RM), and a non-activity control situation (CONT). The CG was evaluated before, during, and immediately after the experimental situations.
Results
Both MOD and HIGH promoted a superior reduction of CG than CONT in NIT (−37 vs. −33 vs. −4 mg/dl, respectively,
p
 < 0.01). Conversely, in RT-sessions, CG reduction was not statistically different when compared to CONT in IT (−51 vs. −45 vs. −20 mg/dl, respectively,
p
 > 0.05). The higher glycemic reduction was found immediately after rather than during the RT session (
p
 < 0.05). In both RT-sessions, pre-exercise CG levels were directly related to CG reduction (
p
 < 0.01).
Conclusions
A single acute RT-session reduces CG, regardless of intensity, in NIT individuals. In IT individuals, the RT-session did not induce an additional effect on CG. Moreover, participants with the highest pre-exercise CG levels were the most benefited ones by RT-session in reducing glycemia.