Spray-dried extract of Phyllanthus niruri L. reduces mucosal damage in rats with intestinal inflammation

Phyllanthus niruri L. belongs to the Euphorbiaceae, and is known by the common name of ‘stonebreaker’ in Brazil. Some species within the Phyllanthus genus are widely used in traditional medicine to counteract different types of anti‐inflammatory diseases. Objectives In this study, the preventive int...

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Bibliographic Details
Published in:	Journal of pharmacy and pharmacology Vol. 67; no. 8; pp. 1107 - 1118
Main Authors:	Melo, Maryanne Nunes de, Soares, Luiz Alberto Lira, Porto, Cynthia Raquel da Costa, Araújo, Aurigena Antunes de, Almeida, Maria das Graças, Souza, Tatiane Pereira de, Petrovick, Pedro Ros, Araújo Júnior, Raimundo Fernandes de, Guerra, Gerlane Coelho Bernardo
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-08-2015
Subjects:	Animals anti-inflammatory Anti-Inflammatory Agents - pharmacology antioxidant Antioxidants - pharmacology colitis Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology Dose-Response Relationship, Drug Female Genes, p53 - drug effects Glutathione - metabolism Inflammation - drug therapy Interferon-gamma - drug effects Intestines - drug effects Intestines - pathology Malondialdehyde - metabolism Phyllanthus Phyllanthus niruri Plant Extracts - pharmacology Rats Rats, Wistar Tumor Necrosis Factor-alpha - drug effects Phyllanthus niruri anti-inflammatory antioxidant colitis rats
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