Intracellularly-Retained Decorin Lacking the C-Terminal Ear Repeat Causes ER Stress

Decorin, a small leucine-rich proteoglycan (SLRP), is involved in the pathophysiology of human congenital stromal corneal dystrophy (CSCD). This disease is characterized by corneal opacities and vision impairment. In reported cases, the human gene encoding decorin contains point mutations in exon 10...

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Bibliographic Details

Published in:	The American journal of pathology Vol. 183; no. 1; pp. 247 - 256
Main Authors:	Chen, Shoujun, Sun, Mei, Iozzo, Renato V, Kao, Winston W.-Y, Birk, David E
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-07-2013
Subjects:	Pathology
Online Access:	Get full text
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