Intrathecal IgM synthesis in neurologic diseases: Relationship with disability in MS

The authors studied the intrathecal IgM synthesis (ITMS) in paired sera and CSF samples from 65 patients with MS, 28 with CNS infection, 40 with other neurologic diseases and eight control subjects. ITMS was found in 30 patients with MS and in 20 with CNS infection, but not in patients with other ne...

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Bibliographic Details
Published in:	Neurology Vol. 58; no. 5; pp. 824 - 826
Main Authors:	VILLAR, L. M, MASJUAN, J, GONZALEZ-PORQUE, P, PLAZA, J, SADABA, M. C, ROLDAN, E, BOOTELLO, A, ALVAREZ-CERMENO, J. C
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins 12-03-2002
Subjects:	Adult Biological and medical sciences Central Nervous System Infections - blood Central Nervous System Infections - cerebrospinal fluid Central Nervous System Infections - immunology Disability Evaluation Female Humans Immunoglobulin M - blood Immunoglobulin M - cerebrospinal fluid Male Medical sciences Multiple Sclerosis - blood Multiple Sclerosis - cerebrospinal fluid Multiple Sclerosis - immunology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Handicap Human Oligoclonal immunoglobulin Nervous system diseases Multiple sclerosis Prognosis Biological marker Cerebrospinal fluid IgM Inflammatory disease Disability Immunological investigation Protein synthesis Central nervous system disease Serum Predictive factor
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