Dual Role of Vinyl Sulfonamides as N‐Nucleophiles and Michael Acceptors in the Enantioselective Synthesis of Bicyclic δ‐Sultams

A new methodology for the synthesis of enantiomerically enriched bicyclic δ‐sultams is described, involving an initial organocatalytic intramolecular aza‐Michael reaction of vinyl sulfonamides bearing a conjugated ketone at a remote position. The resulting Michael adducts were then subjected to an i...

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Bibliographic Details
Published in:Advanced synthesis & catalysis Vol. 360; no. 15; pp. 2885 - 2893
Main Authors: Mulet, Cristina, Escolano, Marcos, Llopis, Sebastián, Sanz, Sergio, Ramírez de Arellano, Carmen, Sánchez‐Roselló, María, Fustero, Santos, del Pozo, Carlos
Format: Journal Article
Language:English
Published: Heidelberg Wiley Subscription Services, Inc 06-08-2018
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