Intracameral injection of tissue plasminogen activator to treat severe postoperative fibrinous reaction in iridocorneal endothelial syndrome

Iridocorneal endothelial (ICE) syndrome is a primary endothelial abnormality that can cause a spectrum of iris changes, corneal edema, and glaucoma. Glaucoma secondary to ICE is difficult to manage because of the inflammatory reaction and fibrosis it can cause. We present a case of postoperative fib...

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Bibliographic Details
Published in:	Digital journal of ophthalmology Vol. 19; no. 2; pp. 21 - 23
Main Authors:	Hong, Bryan K, Francis, Brian A
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Eye and Ear Infirmary 2013
Subjects:	Anterior Chamber Case Reports Cataract Extraction - adverse effects Female Fibrinolysis - drug effects Fibrinolytic Agents - administration & dosage Humans Injections, Intraocular Iridocorneal Endothelial Syndrome - surgery Lens Implantation, Intraocular - adverse effects Middle Aged Postoperative Complications - drug therapy Tissue Plasminogen Activator - administration & dosage Treatment Outcome
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Summary:	Iridocorneal endothelial (ICE) syndrome is a primary endothelial abnormality that can cause a spectrum of iris changes, corneal edema, and glaucoma. Glaucoma secondary to ICE is difficult to manage because of the inflammatory reaction and fibrosis it can cause. We present a case of postoperative fibrinous reaction following endoscopic cyclophotocoagulation in ICE that caused aqueous tube shunt occlusion and high intraocular pressure. The condition was successfully managed with tissue plasminogen activator.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1542-8958 1542-8958
DOI:	10.5693/djo.02.2013.02.002