Synthesis and Properties of 3-Substituted 2H-Chromen-2-ones

• Published in: Russian journal of organic chemistry Vol. 56; no. 7; pp. 1123 - 1131
• Main Authors: Dyachenko, I. V., Dyachenko, V. D., Dorovatovsky, P. V., Khrustalev, V. N., Nenaidenko, V. G.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-07-2020; Springer Nature B.V
• Subjects: Acetates; Aromatic compounds; Chemistry; Chemistry and Materials Science; Condensates; Organic Chemistry; Substitutes; X ray analysis; aryl-3-sulfanylidenepropanamide; 2; chromen-2-one (coumarin); 3-amino; X-ray analysis; ethyl 3-amino-3-sulfanylidenepropanoate; methoxyacetoacetanilide; ethyl 2-(1,3-thiazol-2-yl)acetate
• ISSN: 1070-4280; 1608-3393
• DOI: 10.1134/S1070428020070015

The condensation of salicylaldehyde with CH acids [
p
-methoxyacetoacetanilide, ethyl 3-amino-3-sulfanylidenepropanoate, 3-amino-
N
-aryl-3-sulfanylidenepropanamides, and ethyl 2-(1,3-thiazol-2- and -4-yl)acetates] afforded 3-substituted chromen-2-ones. Some properties of the products were studied. The structures of 3-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2
H
-chromen-2-one, 2-oxo-2
H
-chromene-3-carboxamide, and 2-imino-
N
-(2-methoxyphenyl)-2
H
-chromene-3-carboxamide were determined by X-ray analysis.