Liver damage associated with Minocycline use in acne: A systematic review of the published literature and pharmacovigilance data

Minocycline is an antibacterial drug used in the treatment of acne. Concern has been expressed over the possibility of severe adverse reactions to minocycline, including hepatitis. This study set out to identify and characterise reported cases of hepatotoxicity associated with the use of minocycline...

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Bibliographic Details
Published in:	Drug safety Vol. 23; no. 4; pp. 333 - 349
Main Authors:	LAWRENSON, Ross A, SEAMAN, Helen E, SUNDSTRÖM, Anders, WILLIAMS, Timothy J, FARMER, Richard D. T
Format:	Journal Article
Language:	English
Published:	Auckland Adis international 01-10-2000
Subjects:	acne Acne Vulgaris - complications Acne Vulgaris - drug therapy Adolescent Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Biological and medical sciences Chemical and Drug Induced Liver Injury - pathology Drug toxicity and drugs side effects treatment Fatal Outcome Female Humans liver diseases Male Medical sciences minocycline Minocycline - adverse effects Minocycline - therapeutic use Pharmacology. Drug treatments Product Surveillance, Postmarketing Toxicity: digestive system World Health Organization Human Skin disease Toxicity Acne Liver Tetracycline derivatives Oral administration Hepatic disease Review Pharmacovigilance Antibiotic Chemotherapy Treatment Minocycline Digestive diseases Antibacterial agent Bibliographic review
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