Thyrotropin receptor antisera for the detection of immunoreactive protein species in retroocular fibroblasts obtained from patients with Graves' ophthalmopathy

Autoimmunity against the TSH receptor (hTSH-R) is known to be the proximate cause of thyroidal activation in Graves' disease, but has not been definitively linked to extrathyroidal manifestations of this disorder, such as ophthalmopathy and pretibial myxedema. In an effort to increase our knowl...

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Bibliographic Details
Published in:	The journal of clinical endocrinology and metabolism Vol. 78; no. 6; p. 1384
Main Authors:	Burch, H B, Sellitti, D, Barnes, S G, Nagy, E V, Bahn, R S, Burman, K D
Format:	Journal Article
Language:	English
Published:	United States 01-06-1994
Subjects:	Amino Acid Sequence Animals Cells, Cultured Enzyme-Linked Immunosorbent Assay Eye - immunology Eye - metabolism Fibroblasts - immunology Fibroblasts - metabolism Fibroblasts - pathology Fluorescent Antibody Technique Graves Disease - immunology Graves Disease - surgery Humans Immune Sera Immunoblotting Immunoenzyme Techniques Molecular Sequence Data Ophthalmologic Surgical Procedures Peptides - chemical synthesis Peptides - immunology Rabbits - immunology Receptors, Thyrotropin - analysis Receptors, Thyrotropin - immunology Swine Thyroid Gland - cytology Thyroid Gland - metabolism
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