Biallelic Neutrophil Na-Antigen System Is Associated With a Polymorphism on the Phospho-Inositol-Linked Fcγ Receptor III (CD16)

Neutrophils express two distinct types of receptor for the Fc region of IgG, FcRII and FcRIII, in amounts of 10,000 to 20.000 FcRII (40 Kd) and 100,000 to 200,000 FcRIII (50 to 80 Kd) per neutrophil. We showed that the FcRIII exhibits genetically determined heterogeneity, detectable by differences i...

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Bibliographic Details
Published in:	Blood Vol. 75; no. 1; pp. 213 - 217
Main Authors:	Huizinga, Tom W.J., Kleijer, Marion, Tetteroo, Pedro A.T., Roos, Dirk, Borne, Albert E.G. Kr. von dem
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-01-1990
Subjects:	Antibodies, Monoclonal - immunology Antigens, CD - genetics Antigens, CD - immunology Antigens, CD - metabolism Antigens, Differentiation - genetics Antigens, Differentiation - immunology Antigens, Differentiation - metabolism Electrophoresis, Polyacrylamide Gel Glycolipids - metabolism Glycosylphosphatidylinositols Humans Immunoglobulin G - metabolism Neuraminidase - pharmacology Neutrophils - immunology Phosphatidylinositols - metabolism Polymorphism, Genetic Receptors, Fc - genetics Receptors, Fc - immunology Receptors, Fc - metabolism Receptors, IgG Type C Phospholipases - metabolism
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