Spectroscopic, structural characterization and magnetic studies of Cu(II)-sulfathiazole complex with 1,10-Phenanthroline and N-(2-hydroxyethyl)-Ethylenediamine ligands

• Published in: Journal of molecular structure Vol. 1202; p. 127220
• Main Authors: Öztürk, Filiz, Aycan, Tuğba, Çon, Ahmet Hilmi
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15-02-2020
• Subjects: Antimicrobial activity; EPR; FT-IR spectroscopy; Sulfathiazole; X-ray crystal structure; Antimicrobial activity; X-ray crystal structure; Sulfathiazole; FT-IR spectroscopy; EPR
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2019.127220

Cu(II)-sulfathiazole (Hstz:4-amino-N-(1,3-thiazol-2-yl) benzene sulfonamide) complex with phen (1,10-Phenanthroline) and Hydeten (N-(2-hydroxyethyl)-Ethylenediamine) has been synthesized and characterized by single crystal X-ray diffraction, IR, EPR and UV–Vis spectroscopy, thermal analysis. The [Cu(stz)(Hydeten)(Phen)].(stz)(Phen) complex crystallizes in the orthorhombic space group Pca21, Z = 4. The sulfathiazole anion acts as a monodentate ligand through the thiadiazole N atom contiguous to the deprotonated sulfonamide group. The trigonality factor (τ = (β-α)/60) value of the copper complex is 0.14 and this value expresses having slightly distorted square pyramidal environment of the Cu(II) ions coordination. The powder EPR spectra of Cu(II) complex were recorded at room temperature and liquid nitrogen temperature. The EPR spectral analysis has led to that the ground state of the unpaired electron of copper ion isdx2−y2. As results of the minimum inhibitory concentration (MIC) values obtained as results of the antimicrobial study for stz and complex, it was seen that the metal-stz complex was more effective than free stz.
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•New Cu(II) -sulfathiazole complex with 1,10-Phenanthroline and N-(2-hydroxyethyl)-Ethylenediamine were synthesized.•Structural method (X-ray analysis); exhibits a slightly distorted square pyramidal geometry (τ=0.14).•Spectroscopy properties (IR, UV, EPR) and Thermal Activity.•Antimicrobial activity studies were done.