Medulloblastoma in children and in adults : a comparative study

• Published in: Acta neurochirurgica Vol. 119; no. 1-4; pp. 62 - 67
• Main Authors: MALECI, A, CERVONI, L, DELFINI, R
• Format: Journal Article
• Language: English
• Published: Wien Springer 01-01-1992; New York, NY
• Subjects: Adolescent; Adult; Age Factors; Aged; Biological and medical sciences; Cerebellar Neoplasms - mortality; Cerebellar Neoplasms - pathology; Cerebellar Neoplasms - surgery; Cerebellum - pathology; Cerebellum - surgery; Child; Child, Preschool; Female; Humans; Infant; Male; Medical sciences; Medulloblastoma - mortality; Medulloblastoma - pathology; Medulloblastoma - surgery; Middle Aged; Neoplasm Staging; Neurology; Retrospective Studies; Sex Factors; Survival Rate; Tomography, X-Ray Computed; Tumors of the nervous system. Phacomatoses; Human; Intracranial; Nervous system diseases; Prognosis; Neurospongioma; Histology; Survival; Cerebral disorder; Topography; Adult; Tumor; Child; Age; Comparative study
• ISSN: 0001-6268; 0942-0940
• DOI: 10.1007/BF01541783

We report on the clinical and pathological characters and factors influencing prognosis in a consecutive series of 20 cases of medulloblastoma presenting in childhood and of 20 cases of the tumour presenting in adulthood. The significant differences which emerged were compared with the findings of the largest published series. Medulloblastoma is more often lateral in site and desmoplastic in histology in adults than in children. On our evidence the age at tumour onset not affect survival.