Therapeutic plasma exchange as a treatment modality for steroid refractory acute disseminated encephalomyelitis – A case report

• Published in: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine Vol. 30; no. 1; pp. 16 - 18
• Main Authors: Pandeep, Kaur, Rakesh, Kumar, Mohitpreet, Singh, Prabhjeet, Singh
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01-02-2023
• Subjects: Acute disseminated encephalomyelitis; Encephalomyelitis, Acute Disseminated - drug therapy; Encephalomyelitis, Acute Disseminated - therapy; Female; Humans; Middle Aged; Plasma Exchange - adverse effects; Plasmapheresis; Steroid refractory; Steroids - therapeutic use; Therapeutic plasma exchange; Steroid refractory; Acute disseminated encephalomyelitis; Therapeutic plasma exchange
• ISSN: 1246-7820; 1953-8022
• DOI: 10.1016/j.tracli.2022.08.142

The epidemiology of Dengue fever in the Indian subcontinent has been substantially increased. Acute disseminating encephalomyelitis is a rare complication of dengue and is characterized by multifocal white matter involvement and encephalopathy with neurological deficits. Treatment is usually steroids, IVIG and therapeutic plasma exchange (TPE). We report a case of 46 year old female patient who was a non responder to steroid treatment and successfully treated by TPE.