Analysis of restriction fragment length polymorphism of cytochrome P450 3A43 gene and evaluation of the incidence of CYP3A431B allele in europeoid residents of West Siberia

Analysis of restriction fragment length polymorphism is proposed for detecting CYP3A43 gene c1047 > T mutation. The incidence of this mutation (CYP3A43*1B allele) was evaluated in 102 europeoid residents of West Siberia and it was found to be 12.25%.

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 140; no. 6; pp. 726 - 728
Main Authors:	Shchepotina, E G, Nikishina, M V, Vavilin, V A, Lyakhovich, V V
Format:	Journal Article
Language:	English
Published:	United States Springer Nature B.V 01-12-2005
Subjects:	Adolescent Alleles Aryl Hydrocarbon Hydroxylases - genetics Child Child, Preschool DNA Mutational Analysis European Continental Ancestry Group Female Gene Frequency Genetics, Population Heterozygote Homozygote Humans Infant Male Polymorphism, Genetic Polymorphism, Restriction Fragment Length Siberia Siberia
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Summary:	Analysis of restriction fragment length polymorphism is proposed for detecting CYP3A43 gene c1047 > T mutation. The incidence of this mutation (CYP3A43*1B allele) was evaluated in 102 europeoid residents of West Siberia and it was found to be 12.25%.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-006-0067-6