Minocycline-induced hyperpigmentation: rapid resolution after 755nm alexandrite picosecond laser treatment

Minocycline-induced pigmentation (MIP) is an infrequent complication of minocycline therapy, with four subtypes each with distinct clinical features and histologic staining patterns. MIP may resolve following discontinuation of minocycline therapy or it may persist indefinitely. A 64-year-old Caucas...

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Bibliographic Details
Published in:	Journal of cosmetic and laser therapy Vol. 22; no. 2; pp. 96 - 99
Main Authors:	Rivers, Jason K, Zarbafian, Misha, Vestvik, Brianne, Kawamura, Sara, Ulmer, Marcie, Kuritzky, L Alexandra
Format:	Journal Article
Language:	English
Published:	England 17-02-2020
Subjects:	Anti-Bacterial Agents - adverse effects Humans Hyperpigmentation - chemically induced Lasers, Solid-State - adverse effects Lasers, Solid-State - therapeutic use Low-Level Light Therapy - adverse effects Low-Level Light Therapy - methods Male Middle Aged Minocycline - adverse effects lasers Minocycline pigmentation picosecond
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Summary:	Minocycline-induced pigmentation (MIP) is an infrequent complication of minocycline therapy, with four subtypes each with distinct clinical features and histologic staining patterns. MIP may resolve following discontinuation of minocycline therapy or it may persist indefinitely. A 64-year-old Caucasian male presented with a 6 month history of progressive blue-gray facial pigmentation distributed symmetrically over his face. One session utilizing a 755 nm picosecond Alexandrite laser resulted in immediate and significant clearance of the pigment in all treated areas. Long-term follow-up at 2 years revealed no recurrence of the MIP.
ISSN:	1476-4172 1476-4180
DOI:	10.1080/14764172.2020.1740275