Persistence and 4-year boosting of the bactericidal response elicited by two- and three-dose schedules of MenB-FHbp: A phase 3 extension study in adolescents

The period of heightened risk of invasive meningococcal disease in adolescence extends for >10 years. This study aimed to evaluate persistence of the immune response to the serogroup B meningococcal (MenB) vaccine MenB-FHbp (Trumenba®, Bivalent rLP2086) under two- and three-dose primary vaccinati...

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Bibliographic Details
Published in:	Vaccine Vol. 37; no. 12; pp. 1710 - 1719
Main Authors:	Vesikari, Timo, Østergaard, Lars, Beeslaar, Johannes, Absalon, Judith, Eiden, Joseph J., Jansen, Kathrin U., Jones, Thomas R., Harris, Shannon L., Maansson, Roger, Munson, Samantha, O'Neill, Robert E., York, Laura J., Perez, John L.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 14-03-2019 Elsevier Limited
Subjects:	Adolescents Antigens Booster Complement factor H Data processing Immune response Immune system Immunization Immunogenicity Immunological memory Influenza Interactive systems Invasive meningococcal disease Meningococcal disease Persistence Proteins Psoriasis Quantitation Randomization Safety Schedules Serogroup B Skin diseases Teenagers Vaccination Vaccine Vaccines Young adults United States > US Persistence Vaccine Serogroup B Adolescents Booster Meningococcal disease
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