Cognitive outcome in acute sporadic encephalitis
Acute encephalitis is an inflammation of the brain parenchyma. In the United States, 20,000 cases occur yearly. A variety of cognitive deficits, often the sole cause of disability, may persist after the acute stage. Still, infectious diseases tend to be covered only briefly in neuropsychological han...
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| Published in: | Neuropsychology review Vol. 10; no. 3; pp. 151 - 167 |
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| Language: | English |
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01-09-2000
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| Abstract | Acute encephalitis is an inflammation of the brain parenchyma. In the United States, 20,000 cases occur yearly. A variety of cognitive deficits, often the sole cause of disability, may persist after the acute stage. Still, infectious diseases tend to be covered only briefly in neuropsychological handbooks. Recent literature demonstrates the heterogeneity of both amnestic disorders and the outcome following encephalitides. Herpes Simplex virus (HSV), the most common single etiology of sporadic encephalitis, usually causes the most severe symptoms. Modern antiviral medication, however, seems to improve the cognitive outcome. Much less is known about non-HSV encephalitides, where both mild and severe defects have been observed. This article summarizes the current knowledge and also calls upon a more active neuropsychological research in the area. |
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| AbstractList | Acute encephalitis is an inflammation of the brain parenchyma. In the United States, 20,000 cases occur yearly. A variety of cognitive deficits, often the sole cause of disability, may persist after the acute stage. Still, infectious diseases tend to be covered only briefly in neuropsychological handbooks. Recent literature demonstrates the heterogeneity of both amnestic disorders and the outcome following encephalitides. Herpes Simplex virus (HSV), the most common single etiology of sporadic encephalitis, usually causes the most severe symptoms. Modern antiviral medication, however, seems to improve the cognitive outcome. Much less is known about non-HSV encephalitides, where both mild and severe defects have been observed. This article summarizes the current knowledge and also calls upon a more active neuropsychological research in the area. |
| Author | Hokkanen, L Launes, J |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10983899$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Acute Disease Antiviral Agents - therapeutic use Arachnids Brain research Clinical Trials as Topic Cognition Disorders - virology Cognitive ability Consciousness Dementia - virology Encephalitis Encephalitis - complications Encephalitis - drug therapy Encephalitis - microbiology Encephalitis - psychology Encephalitis - virology Epidemics Etiology Handbooks Herpes simplex Herpes viruses Humans Immunology Infectious diseases Inflammation Memory Memory Disorders - virology Mental Disorders - virology Neuropsychological Tests Neuropsychology Parenchyma Tropical diseases |
| Title | Cognitive outcome in acute sporadic encephalitis |
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