The elusive 8-fluoroadenosine

The synthesis of 8-fluoroadenosine has been accomplished for the first time. The kinetics of deamination of 8-fluoroadenosine with the enzyme adenosine deaminase has also been measured. Graphic

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Published in:	Tetrahedron letters Vol. 39; no. 40; pp. 7231 - 7234
Main Authors:	Barrio, Jorge R., Namavari, Mohammad, Keen, Randy E., Satyamurthy, Nagichettiar
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 01-10-1998
Subjects:	Enzymes and Enzyme reactions Fluorine and compounds Nucleosides Purines Nucleosides Purines Enzymes and Enzyme reactions Fluorine and compounds
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Abstract	The synthesis of 8-fluoroadenosine has been accomplished for the first time. The kinetics of deamination of 8-fluoroadenosine with the enzyme adenosine deaminase has also been measured. Graphic
AbstractList	The synthesis of 8-fluoroadenosine has been accomplished for the first time. The kinetics of deamination of 8-fluoroadenosine with the enzyme adenosine deaminase has also been measured. Graphic
Author	Barrio, Jorge R. Satyamurthy, Nagichettiar Keen, Randy E. Namavari, Mohammad
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Cites_doi	10.1021/ja00840a034 10.1021/bi00222a033 10.1248/cpb.19.104 10.1021/bi952920d 10.1002/qsar.19890080206 10.1021/bi00116a008 10.1021/jm00152a007 10.1021/jm00149a033 10.1021/bi00540a025 10.1111/j.1432-1033.1980.tb04701.x 10.1021/jo960761d 10.1021/jm960881d 10.1002/jps.2600790212 10.1021/ja961456c 10.1039/C39760000430 10.1021/bi00327a011 10.1021/bi00755a023 10.1021/bi00397a027 10.1016/0167-7799(93)90079-O 10.1111/j.1432-1033.1971.tb01587.x 10.1021/ja00988a029 10.1016/0045-2068(87)90011-3 10.1021/bi00316a034 10.1021/ja00452a008 10.1021/ja00853a041 10.1021/bi00271a023 10.1021/bi00775a016 10.1002/jnr.490190212 10.1021/cen-v074n042.p031
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Title	The elusive 8-fluoroadenosine
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