Chiral polypropionate subunit by a chemoenzymatic approach

Enzymatic desymmetrization of meso-4-methyl-3,5- syn-dioxolan-1,3,5,7-tetrol was found to be highly enantioselective leading to both acetylated enantiomers with high enantiomeric excess.

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Bibliographic Details
Published in:Tetrahedron: asymmetry Vol. 9; no. 15; pp. 2559 - 2561
Main Authors: Bonini, C., Chiummiento, L., Funicello, M., Marconi, L., Righi, G.
Format: Journal Article
Language:English
Published: Elsevier Ltd 01-08-1998
Online Access:Get full text
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Description
Summary:Enzymatic desymmetrization of meso-4-methyl-3,5- syn-dioxolan-1,3,5,7-tetrol was found to be highly enantioselective leading to both acetylated enantiomers with high enantiomeric excess.
ISSN:0957-4166
1362-511X
DOI:10.1016/S0957-4166(98)00256-0