Automated radiosynthesis of [ 11 C]CPPC for in-human PET imaging applications

The macrophage colony-stimulating factor 1 receptor (CSF1R) is almost exclusively expressed in microglia, representing a biomarker target for imaging of microglia availability. [ C]CPPC has specific binding affinity to CSF1R and suitable kinetic properties for PET imaging of microglia. However, prev...

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Bibliographic Details

Published in:	American journal of nuclear medicine and molecular imaging Vol. 14; no. 2; pp. 144 - 148
Main Authors:	Jiang, Huailei, Roy, Pritam, Guo, Yan, Muzik, Otto, Woodcock, Eric A
Format:	Journal Article
Language:	English
Published:	United States e-Century Publishing Corporation 01-01-2024
Subjects:	Original radiosynthesis automation PET imaging [11C]CPPC radiopharmaceutical
Online Access:	Get full text
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