One-pot synthesis of β-amino acid derivatives via addition of bis( O-silyl) ketene acetals on iminium salts

Diamond projection of α,β-unsaturated δ-amino acid derivative. We report here our findings on a new and highly efficient strategy for the synthesis of β-amino acids involving the addition of bis( O-silyl) ketene acetals on Mannich type iminium electrophiles.

Bibliographic Details

Published in:	Tetrahedron letters Vol. 48; no. 47; pp. 8277 - 8280
Main Authors:	Moumné, Roba, Denise, Bernard, Parlier, Andrée, Lavielle, Solange, Rudler, Henri, Karoyan, Philippe
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 19-11-2007
Subjects:	Bis( O-silyl) ketene acetals Mannich type iminium electrophiles β-Amino acids β-Amino acids Mannich type iminium electrophiles Bis( O-silyl) ketene acetals
Online Access:	Get full text
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