A novel synthesis and transformations of isothiochroman 2,2-dioxide

A convenient synthesis of isothiochromen-4-one 2,2-dioxide was carried out via cyclisation of o-cyanobenzyl thioacetate by a Thorpe reaction. The reactions of isothiochromen-4-one 2,2-dioxide with nitrogen-containing nucleophilic reagents have been investigated.

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Bibliographic Details
Published in:	Tetrahedron letters Vol. 53; no. 33; pp. 4296 - 4299
Main Authors:	Shyshkina, Olena O., Tkachuk, Tetyana M., Volovnenko, Tetiana A., Volovenko, Yulian M., Zubatyuk, Roman I., Medviediev, Volodymyr V., Shishkin, Oleg V.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 15-08-2012
Subjects:	Cyclisation Isothiochromen-4-one 2,2-dioxide Nitrogen-containing nucleophilic reagents X-ray diffraction X-ray diffraction Nitrogen-containing nucleophilic reagents Cyclisation Isothiochromen-4-one 2,2-dioxide
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Description
Summary:	A convenient synthesis of isothiochromen-4-one 2,2-dioxide was carried out via cyclisation of o-cyanobenzyl thioacetate by a Thorpe reaction. The reactions of isothiochromen-4-one 2,2-dioxide with nitrogen-containing nucleophilic reagents have been investigated.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/j.tetlet.2012.05.163